Results 181 to 190 of about 55,381 (288)

HierAnom‐Path: Zero‐Shot Rare Cancer Detection in Histopathology via Hierarchical Foundation Model Adaptation

open access: yesComputational and Systems Oncology, Volume 6, Issue 1, December 2026.
ABSTRACT Rare cancers collectively represent 20%–25% of all malignancies yet yield fewer than 50 annotated whole‐slide images (WSIs) per subtype in publicly available archives, rendering supervised deep learning inapplicable. We present HierAnom‐Path, to the best of our knowledge, the first framework for zero‐shot rare cancer anomaly detection in ...
Noora Saleem Jumaah   +5 more
wiley   +1 more source

Deletion of Astrocytic TNFR1 Attenuates Hyperexcitability and Initiation of Epileptogenesis

open access: yesGlia, Volume 74, Issue 9, September 2026.
Inducible, astrocyte‐specific deletion of TNFR1 reduces basal EEG spectral power. Loss of astrocytic TNFR1 attenuates acute seizure activity in two distinct experimental models of epilepsy. Deletion of TNFR1 in astrocytes limits epilepsy development and hippocampal pathology in a mouse model of temporal lobe epilepsy with hippocampal sclerosis ...
Lukas Henning   +6 more
wiley   +1 more source

Evaluating the Influence of Injury‐Induced Microstructural Variations on the Efficacy of a Diffusion MRI‐Derived Axon Diameter Surrogate

open access: yesMagnetic Resonance in Medicine, Volume 96, Issue 3, Page 1355-1364, September 2026.
ABSTRACT Purpose To investigate the utility of a recently demonstrated diffusion MRI derived axon diameter surrogate measure (∆D⟂) under pathologic conditions induced by a spinal cord injury model. Methods Contusion injuries were performed on the thoracic–lumbar spinal cord of adult male rats.
Hannah E. Alderson   +4 more
wiley   +1 more source

Comprehensive review of the cerebral aqueduct: anatomy, embryology, imaging, genetics, molecular, and pathology. [PDF]

open access: yesAnat Cell Biol
Dituri G   +11 more
europepmc   +1 more source

The role of vascular risk factors in white matter tract microstructure: a multi‐cohort study in older adults

open access: yesAlzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION Vascular risk factors (VRFs) contribute to white matter microstructural degeneration, but their tract‐specific contributions are unclear. We assessed the independent associations of four major VRFs with white matter microstructure in a large, multi‐cohort study.
James D. LeFevre   +36 more
wiley   +1 more source

Postsurgical Seizure Outcome for Epilepsy Patients According to Histopathological Diagnosis: A Single-Center Experience. [PDF]

open access: yesNeuropsychiatr Dis Treat
Chen R   +11 more
europepmc   +1 more source

MicroRNAs in Spinal Cord Injury: Molecular and Translational Insights

open access: yesBrain and Behavior, Volume 16, Issue 8, August 2026.
MicroRNAs (miRNAs) modulate secondary injury cascades following spinal cord injury (SCI), including inflammation, oxidative stress, apoptosis, and demyelination. Key miRNAs such as miR‐21, miR‐124, miR‐219, and miR‐223 exert neuroprotective effects by regulating astrocytic response, axon regeneration, and remyelination.
Seyyedeh Fahimeh Talebi   +3 more
wiley   +1 more source

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