Results 61 to 70 of about 8,017 (310)

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Dynamics of a damped quintic wave equation with time-dependent coefficients

AIMS Mathematics
We present a comprehensive investigation of the long-term dynamics generated by a semilinear wave equation with time-dependent coefficients and quintic nonlinearity on a bounded domain subject to Dirichlet boundary conditions.
Feng Zhou, Hongfang Li , Kaixuan Zhu , Xin Li   +3 more
doaj   +1 more source

Global attractors for the extensible thermoelastic beam system

Journal of Differential Equations, 2009
This work is focused on the dissipative system describing the dynamics of an extensible thermoelastic beam, where the dissipation is entirely contributed by the second equation ruling the evolution of the temperature. Under natural boundary conditions, we prove the existence of bounded absorbing sets.
GIORGI, Claudio, NASO, MARIA GRAZIA, PATA V., POTOMKIN M.   +3 more
openaire   +4 more sources

Dissipative flows, global attractors and shape theory [PDF]

Topology and its Applications, 2019
14 pages, 1 figure.
Barge Yáñez, Héctor, Rodríguez Sanjurjo, José Manuel   +1 more
openaire   +4 more sources

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Global attractor for a class of nonlinear lattices

Journal of Mathematical Analysis and Applications, 2010
AbstractWe consider a class of nonlinear lattices with nonlinear damping(0.1)u¨n(t)+(−1)pΔpun(t)+αun(t)+h(un(t))+g(n,u˙n(t))=fn, where n∈Z, t∈R+, α is a real positive constant, p is any positive integer and Δ is the discrete one-dimensional Laplace operator.
Jáuber C. Oliveira, Jardel Morais Pereira   +1 more
openaire   +2 more sources

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

Global attractors for a class of degenerate diffusion equations

Electronic Journal of Differential Equations, 2003
In this paper we give two existence results for a class of degenerate diffusion equations with p-Laplacian. One is on a unique global strong solution, and the other is on a global attractor.
Shingo Takeuchi, Tomomi Yokota
doaj  

Uncovering the Underlying Mechanisms of Cancer Metabolism through the Landscapes and Probability Flux Quantifications

iScience, 2020
Summary: Cancer metabolism is critical for understanding the mechanism of tumorigenesis, yet the understanding is still challenging. We studied gene-metabolism regulatory interactions and quantified the global driving forces for cancer-metabolism ...
Wenbo Li, Jin Wang
doaj  

Asymptotic behavior for second order lattice dynamical systems

Discrete Dynamics in Nature and Society, 2001
We consider the existence of the global attractor for a second order lattice dynamical systems.
Shengfan Zhou
doaj   +1 more source