Results 61 to 70 of about 3,182 (259)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Global boundedness in a two-dimensional chemotaxis system with nonlinear diffusion and singular sensitivity

Advances in Nonlinear Analysis
In this study, we investigate the two-dimensional chemotaxis system with nonlinear diffusion and singular sensitivity: ut=∇⋅(uθ−1∇u)−χ∇⋅uv∇v,x∈Ω,t>0,vt=Δv−v+u+g(x,t),x∈Ω,t>0,(∗)\left\{\begin{array}{ll}{u}_{t}=\nabla \cdot \left({u}^{\theta -1}\nabla u ...
Ren Guoqiang, Zhou Xing
doaj   +1 more source

Global existence and boundedness in a reaction–diffusion–taxis system with three species

Advances in Difference Equations, 2018
The global existence and boundedness of a reaction–diffusion–taxis system with three interacting species, among which two species consist of predators competing for one species of prey, are investigated.
Xue Xu, Yong Wang
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Global Existence and Boundedness of the Solution for a Blood Oxygenation Model

Journal of Mathematical Analysis and Applications, 1994
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Stability analysis for a rational difference equation

Arab Journal of Basic and Applied Sciences, 2020
Most qualitative behaviours of difference equations are rapidly investigated nowadays. This can be attributed to the fact that it is often sophisticated to construct the exact solutions of most difference equations. This article is written to analyse the
M. B. Almatrafi, Marwa M. Alzubaidi
doaj   +1 more source

A global Tb Theorem for compactness and boundedness

, 2017
We prove a Tb Theorem that characterizes all Calderon-Zygmund operators that extend compactly on L^p(R^n ...
openaire   +2 more sources

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Boundedness and finite-time blow-up for the chemotaxis system with indirect signal production and flux limitation

Advances in Nonlinear Analysis
In this work, we consider a flux-limited chemotaxis model with indirect signal production and nonlinear diffusion,ut=∇⋅(D(u)∇u)−∇⋅(uf(|∇v|2)∇v)−k1u+k2w,x∈Ω,t>0,0=Δv−μ(t)+w,x∈Ω,t>0,wt=Δw−λ1w+λ2u,x∈Ω,t>0 $$\begin{cases}_{t}=\nabla \cdot \left(D\left(u ...
Tu Xinyu, Mu Chunlai, Minghua Zhang
doaj   +1 more source