Results 81 to 90 of about 1,296,781 (299)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Disease Burden of Glaucoma in China: Findings from the Global Burden of Disease 2019 Study

Clinical Epidemiology, 2022
Yi Sun,1,* Aiming Chen,2,* Minjie Zou,3,* Zhenzhen Liu,3 Charlotte Aimee Young,4 Danying Zheng,3 Guangming Jin3 1Department of Ophthalmology, Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510630, People’s Republic of China ...
Sun Y, Chen A, Zou M, Liu Z, Young CA, Zheng D, Jin G   +6 more
doaj  

Spatial analysis of neglected diseases in Brazil, 2007 to 2009

Tempus Actas de Saúde Coletiva, 2016
This paper aims to describe a set of epidemiological information regarding the spatial distribution of selected neglected diseases in Brazil from 2007 to 2009 and health care infrastructure and socio-economic indicators 2010.
Joyce Mendes de Andrade Schramm, Mônica Rodrigues Campos, Isabel Cristina Martins Emmerick, Luiz Villarinho pereira Mendes, Jurema Corrêa Mota, Sérgio Henrique Almeida Silva Junior   +5 more
doaj   +1 more source

Global Burden of Disease and Economic Growth [PDF]

Relationships between health and economic prosperity or economic growth are difficult to assess. The direction of the causality is often questioned and the subject of a vigorous debate.
Alassane Drabo, Martine Audibert, Pascale Combes Motel   +2 more
core  

The International Response to Climate Change: An Agenda for Global Health [PDF]

, 2009
As the international community negotiates a successor to the Kyoto Protocol of the United Nations Framework Convention on Climate Change (UNFCCC), there is new reason to hope that meaningful action might be taken to prevent devastating climate change ...
Gostin, Lawrence O., Wiley, Lindsay F.
core   +1 more source

World Health Organization Global Estimates and Regional Comparisons of the Burden of Foodborne Disease in 2010 [PDF]

, 2015
Illness and death from diseases caused by contaminated food are a constant threat to public health and a significant impediment to socio-economic development worldwide.
Adegoke, Gabriel O., Afshari, Reza, Alasfoor, Deena, Angulo, Frederick J., Aspinall, Willy, Baines, Janis, Balakrishnan, Kalpana, Bellinger, David C., Bolger, P. Michael, Buchanan, Robert, Budke, Christine, Caipo, Marisa L., Carabin, Hélène, Cawthorne, Amy, Chaicumpa, Wanpen, Cole, Dana, Cooke, Roger M., Cravioto, Alejandro, Crump, John A., de Noordhout, Charline Maertens, de Silva, Nilanthi R., Devleesschauwer, Brecht, Döpfer, Dörte, Ehiri, John E., El-Jardali, Fadi, Fazil, Aamir, Ferreccio, Catterina, Fischer-Walker, Christa, Fèvre, Eric M., Fürst, Thomas, Gargouri, Neyla, Gibb, Herman J., Haagsma, Juanita A., Hald, Tine, Hall, Aron J., Hall, Gillian, Hamza, Wan Mansor Bin, Havelaar, Arie H., Henao, Olga, Hoffmann, Sandra, Jensen, Helen, Jessani, Nasreen, Kasuga, Fumiko, Keddy, Karen H., Kirk, Martyn D., Koopmans, Marion P G, Lake, Robin J., Lanata, Claudio F., Lei, Haicho, Levine, Myron M., Liu, Xiumei, Majowicz, Shannon, Manyindo, Ben, Mathers, Colin, McDonald, Scott A., Nasinyama, George, Ongolo-Zogo, Pierre, Pires, Sara, Pitt, John I., Praet, Nicolas, Rokni, Mohammad B., Scallan, Elaine, Speybroeck, Niko, Sripa, Banchob, Sripa, Banchob, Stein, Claudia, Thomas, M. Kate, Torgerson, Paul R., van Leeuwen, Rolaf, Verger, Philippe, Verhoef, Linda, Willingham, Arve Lee, Wu, Felicia, Zeilmaker, Marco, Zhou, Xiao Nong   +74 more
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Living in interesting times - Challenging protein metabolism in the era of the epidemiological shift [PDF]

, 2016
The recently released results of the Global Burden of Disease, Injuries, and Risk Factor study 2013 reveal that during the past 23 years, metabolic and behavioral risk factors, including high BMI, increased their impact on global mortality and disability-
Laviano, Alessandro
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source