Results 101 to 110 of about 6,711,226 (342)

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Traceable and Scalable Food Balance Sheets from Agricultural Commodity Supply and Utilization Accounts (2010–2022)

Scientific Data
The Food Balance Sheets (FBS), compiled by the Food and Agriculture Organization (FAO), serve as a cornerstone dataset for studies on agricultural development, food security, and dietary health, providing a broad overview of global and regional food ...
Xin Zhao, Maksym Chepeliev, Neus Escobar, Matthew T. Binsted, Pralit Patel, Page Kyle, Marshall A. Wise   +6 more
doaj   +1 more source

Prediction of ozone effects on net ecosystem production of Norway spruce forest

iForest - Biogeosciences and Forestry, 2018
Future ground-level concentrations of phytotoxic ozone are projected to grow in the Northern Hemisphere, at a rate depending on emission scenarios. We explored the likely changes in net ecosystem production (NEP) due to the increasing concentration of ...
Jurán S, Edwards-Jonášová M, Cudlín P, Zapletal M, Šigut L, Grace J, Urban O   +6 more
doaj   +1 more source

Conservation Letter: Effects of Global Climate Change on Raptors1 [PDF]

, 2023
Marisela Martínez‐Ruiz, Cheryl R. Dykstra, Travis L. Booms, Michael T. Henderson   +3 more
openalex   +1 more source

Global Demographic Change: Dimensions and Economic Significance [PDF]

Transitions from high mortality and fertility to low mortality and fertility can be beneficial to economies as large baby boom cohorts enter the workforce and save for retirement, while rising longevity has perhaps increased both the incentive to invest ...
David Canning, David E. Bloom
core  

Human dimensions of global environmental change: A review of frameworks and research gaps. [PDF]

, 2005
This review of current knowledge in, and development of, priorities for research into the human dimensions of global environmental change has been conducted to assist the Foundation for Research Science and Technology to formulate their research needs ...
Campbell, John, Gillespie, Alexander, Scrimgeour, Frank, Urich, Peter   +3 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Gaming the unknown: learning to differentiate and respond to uncertainty through a serious game

npj Climate Action
Effective climate adaptation planning requires understanding various sources and types of uncertainty. We investigated how a serious game can improve participants’ understanding of uncertainty in adaptation decision-making.
Wout Jan-Willem Sommerauer, Bregje van der Bolt, Saskia Werners, Wouter Julius Smolenaars, Marlies van Ree, Fulco Ludwig   +5 more
doaj   +1 more source

Global fractional urban changes at 1km under diverse SSP-RCP scenarios throughout 2100

, 2023
Wanru He, Xuecao Li, Yuyu Zhou, Zitong Shi, Guojiang Yu, Tengyun Hu, Yixuan Wang, Jianxi Huang, Tiecheng Bai, Zhongchang Sun, Xiaoping Liu, Peng Gong   +11 more
openalex   +1 more source