Results 141 to 150 of about 11,636,692 (262)

An updated definition of global health

open access: yes
The most cited definition of global health, published in The Lancet in 2009, defines global health as "an area for study, research, and practice that places a priority on improving health and achieving equity in health for all people worldwide".
Waggett, Caryl E.   +15 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Issues : global change - climate change and variability / risk - vulnerability / research - capacity building - governance / science - communication - decision processes

open access: yes, 2007
PowerPoint presentationThe presentation covers precipitation patterns and climate anomalies in Brazil. It then reviews partnerships with climate change research groups in North and South America.
Inter-American Institute for Global Change Research (IAI)
core   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

The Impacts of Climate Change on Human Health in the United States : a Scientific Assessment

open access: yes, 2016
"The purpose of this assessment is to provide a comprehensive, evidence-based, and, where possible, quantitative estimation of observed and projected climate change related health impacts in the United States.
U.S. Global Change Research Program
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

The forest of knowledge under global change. [PDF]

open access: yesNature
Cámara-Leret R   +2 more
europepmc   +1 more source

Synthesis and Assessment Product

open access: yes
This brochure identifies four types of abrupt climate change that would pose major risks to global health, security, and the ...
U.S. Global Change Research Program
core  

Climate and Global Change Interagency Inventory Data Sheet

open access: yes, 2002
The Climate and Global Change Interagency Inventory Data Sheet is a working document (dated August 2002) that includes information provided by federal agencies regarding their climate and global change research ...
Climate Change Science Program
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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