Results 141 to 150 of about 240,324 (313)

Toilets unblocked : A literature review of school toilets [PDF]

, 2013
Burton, Sarah
core  

Inferring Gene Regulatory Networks From Single‐Cell RNA Sequencing Data by Dual‐Role Graph Contrastive Learning

Advanced Science, EarlyView.
RegGAIN is a novel and powerful deep learning framework for inferring gene regulatory networks (GRNs) from single‐cell RNA sequencing data. By integrating self‐supervised contrastive learning with dual‐role gene representations, it consistently outperforms existing methods in both accuracy and robustness.
Qiyuan Guan, Jiating Yu, Jieyi Pan, Fan Yuan, Jiadong Ji, Rusong Zhao, Zhi‐Ping Liu, Bingqiang Liu, Ling‐Yun Wu, Duanchen Sun   +9 more
wiley   +1 more source

Creating Lifelong Relationships: Children’s Connections to Characters

WOW Stories, 2007
Kathryn Tompkins
doaj  

Exploring Oral Health Challenges and Barriers to Dental Care Among Children in Cabo Verde: A Qualitative Study. [PDF]

Public Health Chall
Ilozumba O, Visser MW, de Soet JJH, Volgenant CMC.   +3 more
europepmc   +1 more source

Genetic Diagnosis and Discovery Enabled by Large Language Models

Advanced Science, EarlyView.
We demonstrate that large language models (LLMs) can facilitate genetic diagnosis and discovery. LLMs were used to solve four types of genetic problems of sequentially increased complexity. An LLM‐based pipeline could analyze genetic variants in the genomic sequences of human hearing loss or rare genetic disease patients and assist in identifying ...
Tao Tu, Khaled Saab, Weida Liu, Zhouqing Fang, Zhuanfen Cheng, Svetolik Spasic, Maja Djurisic, Hiroaki Mohri, Wenlong Ren, Anil Palepu, Juraj Gottweis, Alan Karthikesalingam, Kavita Kulkarni, Annalisa Pawlosky, Devon Bonner, Elijah Kravets, Shruti Marwaha, Hector R. Mendez, Matthew T. Wheeler, Jonathan A. Bernstein, Undiagnosed Diseases Network, Cheng‐Yu Tsai, Chen‐Chi Wu, Konstantina M. Stankovic, Vivek Natarajan, Gary Peltz   +25 more
wiley   +1 more source

When Literature Discussion Seems to Go Nowhere: Revaluing Teaching and Learning

WOW Stories, 2007
Lisa Thomas
doaj  

Do Children and Parents Agree on the Level of Asthma Control? A Systematic Review. [PDF]

Pediatr Pulmonol
Bousema S, Ossendrijver I, van Zwet ME, Bohnen AM, Bindels PJE, van Tilborg-den Boeft M.   +5 more
europepmc   +1 more source

Cortical Somatostatin Neurons Regulate Seizure Susceptibility via MINAR1/Gαs–cAMP Signaling

Advanced Science, EarlyView.
Our study identifies MINAR1 as a novel regulator of cortical interneuron excitability and seizure susceptibility. MINAR1 is preferentially expressed in SST+ interneurons. Genetic ablation of MINAR1 leads to seizure hypersensitivity, reduced SST+ neuron excitability, and impaired Gαs–cAMP signaling, disrupting the E/I balance.
Wei‐Tang Liu, Zhi‐Bin Hu, Ling Hu, Yu‐Bing Wang, Qiong Zhang, Ning‐Ning Song, Xi‐Yue Liu, Jia‐Yin Chen, Hong‐Wen Zhu, Bing‐Yao Zhou, Yun‐Chao Tao, Li Zhao, Ze‐Xuan Li, Yi‐Wei Li, Jia‐Qi Chen, Si‐Xin Tu, Cong‐Cong Qi, Sai‐Dan Ding, Gang Peng, Lin Xu, Yu‐Qiang Ding   +20 more
wiley   +1 more source

Learning To Mean: Teaching about Refugees

WOW Stories, 2011
Lorraine Wilson
doaj  

Parent emotion regulation difficulties statistically mediate the association between parental adverse childhood experiences and child emotion regulation. [PDF]

Front Glob Womens Health
Freeman SE, Staples AD, Loverich TM, Hannapel M, Lawler JM.   +4 more
europepmc   +1 more source