Results 61 to 70 of about 783,564 (331)

Sickle cell disease among children in Africa: An integrative literature review and global recommendations

open access: yesInternational Journal of Africa Nursing Sciences, 2015
AbstractSickle cell disease (SCD) is a genetic blood disorder affecting red blood cells, with high morbidity and mortality rates. The United Nations has recognized SCD as a global public health concern, and the World Health Organization (WHO) recommends that 50% of member states will have established SCD control programs by 2020 (World Health ...
Lucky L. Mulumba, Lynda Wilson
openaire   +3 more sources

Pneumococcus and the stress-gradient hypothesis: a trade-off links $R_0$ and susceptibility to co-colonization across countries [PDF]

open access: yesarXiv, 2022
Modern molecular technologies have revolutionized our understanding of bacterial epidemiology, but reported data across different settings remain under-integrated in common theoretical frameworks. Pneumococcus serotype co-colonization, caused by the polymorphic bacteria Streptococcus pneumoniae, has been increasingly investigated in recent years. While
arxiv  

Analysis of Temperature and Stress Distribution on the Bond Properties of Hybrid Tailored Formed Components

open access: yesAdvanced Engineering Materials, EarlyView.
Hybrid materials enable high‐performance components but are challenging to process. This study explores an inductive heating concept with spray cooling for steel–aluminum specimens in a two‐step process including friction welding and cup backward extrusion.
Armin Piwek   +7 more
wiley   +1 more source

Mesenchymal Stem Cells‐Derived Extracellular Vesicles Mimetics as Osteoinductive Mediators for Bone Healing

open access: yesAdvanced Functional Materials, EarlyView.
Mesenchymal stem cell‐derived nanoghosts (MSC‐NGs) mimic naturally secreted extracellular vesicles (MSC‐EVs) in structure and physicochemical properties but can be synthesized at more translatable yields. As osteogenic agents, MSC‐NGs demonstrate superior outcomes compared to MSC‐EVs.
Antoine Karoichan   +4 more
wiley   +1 more source

Biodegradable, Humidity‐Insensitive Mask‐Integrated E‐Nose for Sustainable and Non‐Invasive Continuous Breath Analysis

open access: yesAdvanced Functional Materials, EarlyView.
This study introduces a paper‐based biodegradable, humidity‐insensitive e‐nose for real‐time breath analysis, addressing challenges in existing technologies such as humidity interference, high costs, and environmental impact. Featuring hydrophobic polymer coatings, these sensors reliably detect VOCs even in high‐moisture environments.
Indrajit Mondal   +2 more
wiley   +1 more source

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

open access: yesAdvanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan   +4 more
wiley   +1 more source

Critical appraisal on mitochondrial dysfunction in Alzheimer’s disease

open access: yesAGING MEDICINE, Volume 5, Issue 4, Page 272-280, December 2022., 2022
Amyloid plaques deposit on neurons in case of Alzheimer's Disease. Mitochondria play a vital role in pathogenesis of Alzheimer's Disease. Mitochondrial dysfunction can lead to formation of mPTP, alteration of complexes 1,3 and 4, deficits in bioenergetics with impaired mitochondrial biogenesis. Abstract It is widely recognized that Alzheimer's disease (
Faizan Ahmad, Punya Sachdeva
wiley   +1 more source

In Vivo‐Like Scaffold‐Free 3D In Vitro Models of Muscular Dystrophies: The Case for Anchored Cell Sheet Engineering in Personalized Medicine

open access: yesAdvanced Healthcare Materials, EarlyView.
The scaffold‐free Anchored Cell Sheet Engineering platform is used to create three‐dimensional (3D) in vitro models of skeletal muscle tissue that replicate key features of Duchenne and Myotonic dystrophies. These personalized tissue models, validated by histological, immunostaining, and proteomics analyses, accurately mimic disease phenotypes and ...
Alireza Shahin‐Shamsabadi   +1 more
wiley   +1 more source

Children and the Data Cycle: Rights and Ethics in a Big Data World [PDF]

open access: yesarXiv, 2017
In an era of increasing dependence on data science and big data, the voices of one set of major stakeholders - the world's children and those who advocate on their behalf - have been largely absent. A recent paper estimates one in three global internet users is a child, yet there has been little rigorous debate or understanding of how to adapt ...
arxiv  

Tribenzyl Organic Cations Carried Multidentate X‐Type Lewis Soft Base for High‐Performance Foldable Perovskite Light‐Emitting Diodes

open access: yesAdvanced Materials, EarlyView.
This study proposes tribenzyl organic cation carried multidentate X‐type Lewis soft base to enhance adhesion and passivate defects simultaneously, aiming to achieve foldable and efficient perovskite nanocrystal‐based light‐emitting diodes. The resulting pure red F‐PeLEDs exhibit a recorded high EQE of 16.2% and robust mechanical properties to endure ...
Benzheng Lyu   +9 more
wiley   +1 more source

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