Results 101 to 110 of about 5,203,047 (299)

Rancang Bangun Sistem Monitoring Kehadiran Dosen Berbasis Web Pada STMIK Bina Sarana Global [PDF]

, 2018
Informasi merupakan hal yang penting, kecepatan penyampaian informasi dan akses data juga tidak kalah pentingnya bagi suatu organisasi untuk dapat memenangkan persaingan. STMIK BINA SARANA GLOBAL adalah Perguruan Tinggi yang berlokasi di Jl.
Triono, Triono, Hanafri, Muhammad Iqbal, Luthfiudin, Imam   +2 more
core   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Acerca de la intervención de la universidad en la cooperación al desarrollo de base tecnológica. Algunos casos de agua y saneamiento en la Universidad Politécnica de Madrid

Arte, Diseño e Ingeniería, 2015
ResumenLa comunidad universitaria no podía ser ajena a las actividades de cooperación,cuyo principal objetivo es la transformación de la sociedad en busca de loseternos ideales de lograr una sociedad más justa, más libre, a través del desarrollo global ...
José Antonio Mancebo Piqueras, María del Mar Recio, Christian Polo Castaño, Eneko Muskiz   +3 more
doaj  

Gestion bipartita de la formacion continua

, 1999
Centro de Informacion y Documentacion Cientifica (CINDOC). C/Joaquin Costa, 22. 28002 Madrid.
Oficina Internacional del Trabajo CINTERFOR (Spain), Fundacion para la Formacion Continua - FORCEM, Madrid (Spain)   +1 more
core  

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Global Health Security Branch : advancing global health security [PDF]

The Global Health Security Branch (GHSB) leads CDC\ue2\u20ac\u2122s global health security engagement with other U.S. government agencies and programs, multilateral institutions such as the World Health Organization (WHO) and the World Bank, ministries ...

core  

Optimización global de funciones continuas

, 2011
versión ...
openaire   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Hacia una historia global descolonizada: una perspectiva latinoamericana

Esboços
La historia global está en auge desde hace más de dos décadas. Sin embargo, a diferencia de Europa, Estados Unidos y Asia, donde se puede observar un verdadero “boom” de esta perspectiva, en Latinoamérica no ha tenido tanto impacto hasta ahora; incluso ...
Gabriela de Lima Grecco, Sven Schuster
doaj   +1 more source