Results 71 to 80 of about 5,203,047 (299)

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Transferencia de calor en la colada continua de aceros. I parte. El molde

open access: yesRevista de Metalurgia, 1997
El molde de colada continua cumple la importante función de recibir el acero líquido y permitir que se desarrolle una capa solidificada uniforme y libre de defectos.
C. Cicutti
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Aplikasi Evaluasi Kinerja Dosen di STMIK Bina Sarana Global [PDF]

open access: yes, 2015
Dosen adalah salah satu komponen esensial dalam suatu sistem pendidikan di perguruan tinggi. Peran, tugas, dan tanggungjawab dosen sangat penting dalam mewujudkan tujuan pendidikan nasional, yaitu mencerdaskan kehidupan bangsa, meningkatkan kualitas ...
Sutarman, Sutarman, Simbolon, Mardianton
core   +1 more source

On global continua of solutions bifurcating from zero and infinity of some nonlinear fourth order eigenvalue problems

open access: yesProceedings of the Institute of Mathematics and Mechanics,National Academy of Sciences of Azerbaijan, 2020
Summary: In this paper we consider the nonlinear eigenvalue problems for ordinary differential equations of fourth order. The previously obtained results on global bifurcation of solutions from zero and infinity of these problems in wider classes of functions with fixed oscillation count are established.
openaire   +2 more sources

Objetivos Programa Ejecutivo en Gerenciamiento y Gestión de Negocios en el Mercado Farmacéutico - Modalidad a distancia -

open access: yes, 2014
Universidad de Belgrano. Departamento de estudios de posgrado y educación continua. Objetivos Programa Ejecutivo en Gerenciamiento y Gestión de Negocios en el Mercado Farmacéutico - Modalidad a distancia - Educación Continua ...
Universidad de Belgrano. Departamento de estudios de posgrado y educación continua
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Insider, Outsider or an In-Betweener? Epistemological Reflections of a Legally Blind Researcher on Conducting Cross-National Disability Research

open access: yesScandinavian Journal of Disability Research, 2020
Researchers have long debated the perils and possibilities associated with being an insider or an outsider while conducting qualitative research. This paper revisits this insider-outsider debate by drawing on the experiential insights of a legally blind ...
Gagan Chhabra
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Cancerul glandei mamare – maladia întregii civilazații.

open access: yesBuletinul Academiei de Ştiinţe a Moldovei: Ştiinţe Medicale, 2018
Cancerul glandei mamare (CGM) actualmente reprezintă cea mai frecventă formă de neoplazii la femei, constituind o problemă majoră cu impact global, cauzată de morbiditate și mortalitate înaltă.
Larisa Sofroni
doaj  

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