Results 61 to 70 of about 6,648,849 (356)
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Fermentation, 2023 Strain ST182Gu, isolated from fresh guava fruit, was identified as Enterococcus casseliflavus on the basis of biochemical tests, sugar fermentation reactions (API20Strip), PCR with genus-specific primers, and 16S rRNA sequencing.
Svetoslav Dimitrov Todorov +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
IEEE Access, 2023 Combining skeleton and RGB modalities in human action recognition (HAR) has garnered attention due to their ability to complement each other. However, previous studies did not address the challenge of recognizing fine-grained human-object interaction ...
Akash Ghimire, Vijay Kakani, Hakil Kim
doaj +1 more source
Rate of convergence of attractors of reaction-diffusion equations with nonlinear boundary conditions
, 2020 This paper we study the rate of convergence of the asymptotic dynamics of reaction-diffusion equations with nonlinear Robin boundary conditions. We show how the rate of convergence of the global attractors can be affected by the variation of the ...
Bezerra, Flank David Moraes +1 more
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
The Influence of Human Factors in Flight Training
Hanggong uju uihakoeji, 2023 Purpose: Most aviation accidents are caused by human factors, and in recent years in Korea, human factors have been identified as the cause of 70% of aviation accidents.
Hui-Jin Kim, Jin-Kook Choi
doaj +1 more source
Comparison of Characteristics of a ZnO Gas Sensor Using a Low-Dimensional Carbon Allotrope
Sensors, 2022 Owing to the increasing construction of new buildings, the increase in the emission of formaldehyde and volatile organic compounds, which are emitted as indoor air pollutants, is causing adverse effects on the human body, including life-threatening ...
Jihoon Lee, Jaebum Park, Jeung-Soo Huh
doaj +1 more source
Global convergence of splitting methods for nonconvex composite optimization
, 2015 We consider the problem of minimizing the sum of a smooth function $h$ with a bounded Hessian, and a nonsmooth function. We assume that the latter function is a composition of a proper closed function $P$ and a surjective linear map $\cal M$, with the ...
Li, Guoyin, Pong, Ting Kei
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source