Results 151 to 160 of about 1,146,140 (311)
FEBS Open Bio, EarlyView.In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
全球化脈絡下的教育課題：全球教育 The Educational Topic Within the Globalizing Context Global Education
Journal of Curriculum Studies, 2005 本文首先談及全球化與反全球化思潮及活動，談及「全球教育」是化解全球下議題的要件，並陳述全球教育在歷史發展中遭受政治與宗教的挑戰與回應；第二，筆者將談及全球教育的發展，包括全球教育概念的分析、比較、遷移、發展分期、我國研究發展，以及概念轉變的綜合評析；第三，談到全球教育觀點的變遷與國際概況；第四，談到全球教育的「世界－本土」關係、全球教育的責任、哲理建構的探究等，最後提出全球教育的理想與展望。 This article mainly explored the thoughts and ...
顏佩如 Pey-Ru Yen
doaj
Global Citizenship Education (GCE) in Post-Secondary Institutions: What is protected and what is hidden under the umbrella of GCE? [PDF]
, 2012 In this article, we examine how educating for global citizenship has increasingly become a shared goal of educators and educational institutions interested in expanding their own and their students’ understanding of what it means to claim or to ...
Jorgenson, Shelane, Shultz, Lynette
core +1 more source
Small RNA pathways in mammalian oocytes
FEBS Open Bio, EarlyView.Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
Creating a Global Citizen and Assessing Outcomes [PDF]
, 2011 This article examines development of the field of global citizenship education in postsecondary education in Canada. Analysis centers on the forces of globalization and internationalization as a catalyst for innovation. Plato’s Allegory of the Cave
Brigham, Margaret
core +1 more source
FEBS Open Bio, EarlyView.TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
Education: Tackling the global crisis [PDF]
, 2001 Today 125 million children do not get any formal education at all. This education crisis undermines any chance of rapid progress in human development.
core
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source