Results 141 to 150 of about 13,208,906 (298)
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
An updated definition of global health
The most cited definition of global health, published in The Lancet in 2009, defines global health as "an area for study, research, and practice that places a priority on improving health and achieving equity in health for all people worldwide".
Waggett, Caryl E. +15 more
core +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
全球化脈絡下的教育課題：全球教育 The Educational Topic Within the Globalizing Context Global Education
Journal of Curriculum Studies, 2005 本文首先談及全球化與反全球化思潮及活動，談及「全球教育」是化解全球下議題的要件，並陳述全球教育在歷史發展中遭受政治與宗教的挑戰與回應；第二，筆者將談及全球教育的發展，包括全球教育概念的分析、比較、遷移、發展分期、我國研究發展，以及概念轉變的綜合評析；第三，談到全球教育觀點的變遷與國際概況；第四，談到全球教育的「世界－本土」關係、全球教育的責任、哲理建構的探究等，最後提出全球教育的理想與展望。 This article mainly explored the thoughts and ...
顏佩如 Pey-Ru Yen
doaj
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
This study analyzes geography education in the 2017 Japanese Course of Study for Elementary School Social Studies from three dimensions—content selection, spatial scope, and content organization—and identifies its structural characteristics and ...
You Jung Jun +1 more
core +1 more source
Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source