Results 51 to 60 of about 13,208,906 (298)

Rethinking Global Citizenship through Open Science. The Challange of Game-Based Collaborative Research with Young People

open access: yesRevista Latinoamericana de Tecnología Educativa
A participatory research process, framed within the paradigm of open science, was undertaken to explore how young people understand and engage with global citizenship in the context of the current severe socio-ecological crisis.
Gloria Braga-Blanco   +3 more
doaj   +1 more source

Teacher Futures: Global Reaction to Teacher Shortages in Rural Locations

open access: yesIAFOR Journal of Education, 2022
Upcoming changes in the teacher labor supply will have an impact on nations that provide government-based education for their youth. Faced with a significant global shortfall of educators, most countries have taken steps to incentivize teaching as a ...
Robert Mitchell   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Understanding students’ global interdependence in science instruction

open access: yesJournal of Global Education and Research, 2021
Multiple American educational organizations such as the National Education Association, Association for Supervision and Curriculum Development, and the Council of Chief State School Officers have advocated for globalizing the K-12 curriculum.
Walter Smith
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Global and Development Education and Global Skills

open access: yesEducar, 2020
Development education has its roots in Europe in response to decolonisation and the need for public support and engagement in international development. From these roots, it grew as a field of educational practice to encompass themes of global citizenship, postcolonialism and critical pedagogy.
openaire   +6 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Informal Spaces in Global Citizenship Education [PDF]

open access: yes, 2018
Literature on global citizenship education (GCE) has helped to build a framework of best practice for its implementation and delivery. Creating safe spaces and open environments for teaching, learning and discussion have been widely supported by scholars.
Le Bourdon, M   +2 more
core  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

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