Results 81 to 90 of about 13,208,906 (298)
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
全球教育的重要主題及其課程設計On Key Themes of Global Education and Their
有鑑於全球化的趨勢與衝擊愈來愈明顯,各國紛紛重視國際或全球教育的改革,尤其希望透過課程與教學的調整,培育具備國際觀、全球行動與競爭力的人才。本研究旨在探討全球教育課程的重要主題,並分析我國在國際教育課程設計上的現況與重點。首先,分析全球教育課程的內涵,繼之彙整英國與澳洲的課程設計實例,並進而探討全球教育課程設計的三類模式及其重要主題,包括第一類是透過五大類主題來彰顯全球教育內涵;第二類是透過全球性議題來建立全球公民素養;第三類則是透過合作專案學習來擴展國際視野 ...
林永豐 Yung-Feng Lin
doaj +1 more source
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Investigating Student Use of Technology for Engaged Citizenship in A Global Age
This study undertook a five month qualitative investigation into technology use amongst twelve high school social studies students in two different sites in the Midwestern United States.
Brad M. Maguth
doaj +1 more source
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Mapping the Global Dimension within teaching and learning [PDF]
This chapter attempts to map the Global Dimension of engineering within the academic setting and hence provide some pointers as to how academics can incorporate Global Dimension perspectives and capacities into engineering programmes.
Byrne, Edmond P.
core +1 more source
Teleeducation: Pandemic Proofing Global Education. [PDF]
Michel J +3 more
europepmc +1 more source
Exploring knowledge production and policy shifts in global higher education
Higher education is undergoing significant transformation in response to global pressures such as policy shifts, internationalization, and changing governance models.
Özkan, Metin +2 more
core +1 more source
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Global education movement: English as a second language teachers' perceptions of integrating volatility, uncertainty, complexity, and ambiguity elements in lessons. [PDF]
Yaccob NS, Yunus MM, John DS.
europepmc +1 more source

