Results 111 to 120 of about 5,779,825 (391)

Organizational interactions in global energy governance [PDF]

, 2017
This chapter explores inter-organizational relations in the field of global energy governance. It starts by mapping the policy field of energy governance, the existing literature, and the multilateral energy architecture. It then performs an organization-
Van de Graaf, Thijs
core   +2 more sources

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Exploring the planetary health equity governance supercluster complex

Earth System Governance
The global planetary health equity (PHE) governance architecture can shape government responses to the interrelated challenges of the climate crisis, economic inequality, and poor health. The structure of this architecture has yet to be examined.
Nicholas Frank, Sharon Friel, Megan Arthur   +2 more
doaj  

Doing (and undoing) privilege: evaluating how public policy drives health inequities

Critical Public Health
In an era marked by persistent health inequities, this commentary moves beyond the conventional focus on disadvantage and individual-level interventions to present novel conceptual and analytical thinking that illuminates the role of structurally ...
Ashley Schram, Amy Carrad, Belinda Townsend, Patrick Harris, Fran Baum, Lucie Rychetnik, Steven Allender, Melanie Pescud, Nicholas Frank, Megan Arthur, Sharon Friel   +10 more
doaj   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Utilization of healthcare services among Chinese migrants in Kenya: a qualitative study

BMC Health Services Research, 2019
Background The number of Chinese migrants in Sub-Saharan Africa (SSA) is increasing, which is part of the south-south migration. The healthcare seeking challenges for Chinese migrants in Africa are different from local people and other global migrants ...
Jialing Qiu, Duo Song, Juan Nie, Mengyi Su, Chun Hao, Jing Gu, Yuantao Hao, James N. Kiarie, Michael H. Chung   +8 more
doaj   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Priming attachment and diversity ideologies: Effects on ethnic bias in children's altruistic sharing in a dictator game

Acta Psychologica, 2022
Children often show a positive ingroup bias in altruistic behaviors such as sharing. Insight in factors related to ethnic bias in sharing can help towards understanding the origins of inequality in the distribution of resources in society.
Ymke de Bruijn, Rosanneke A.G. Emmen, Daudi van Veen, Judi Mesman   +3 more
doaj  

Elements of a Theory of Global Governance [PDF]

Glocalism, 2016
After the devastation of World War II, a new international community was built, organized under the newly formed United Nations which oversaw the development of a new legal and institutional framework for the maintenance of peace and security. Maintaining global peace and stability served the purpose of limiting violence, but it was also a prerequisite
openaire   +7 more sources