Results 51 to 60 of about 1,449,938 (284)
Energies, 2021 In this paper, the design procedure and optimization process of a multi-phase flux-switching permanent magnet (FSPM) generator for wind power generation system is investigated.
Feng Li, Xiaoyong Zhu
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
The q-gradient method for global optimization
, 2013 The q-gradient is an extension of the classical gradient vector based on the concept of Jackson's derivative. Here we introduce a preliminary version of the q-gradient method for unconstrained global optimization. The main idea behind our approach is the
Galski, Roberto L. +2 more
core +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Sensors, 2021 To achieve the real-time application of a dynamic programming (DP) control strategy, we propose a predictive energy management strategy (PEMS) based on full-factor trip information, including vehicle speed, slip ratio and slope.
Fenglai Yue +4 more
doaj +1 more source
The True Destination of EGO is Multi-local Optimization
, 2017 Efficient global optimization is a popular algorithm for the optimization of expensive multimodal black-box functions. One important reason for its popularity is its theoretical foundation of global convergence.
Preuss, Mike, Wessing, Simon
core +1 more source
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Calibration of the E3SM Land Model Using Surrogate‐Based Global Optimization
Journal of Advances in Modeling Earth Systems, 2018 Calibration of the Energy Exascale Earth System Model (E3SM), land model (ELMv0) is challenging because of its model complexity, strong model nonlinearity, and significant computational requirements. Therefore, only a limited number of simulations can be
Dan Lu +3 more
doaj +1 more source
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
EOFA: An Extended Version of the Optimal Foraging Algorithm for Global Optimization Problems
ComputationThe problem of finding the global minimum of a function is applicable to a multitude of real-world problems and, hence, a variety of computational techniques have been developed to efficiently locate it.
Glykeria Kyrou +2 more
doaj +1 more source