Results 71 to 80 of about 9,535,029 (378)

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source

EOFA: An Extended Version of the Optimal Foraging Algorithm for Global Optimization Problems

Computation
The problem of finding the global minimum of a function is applicable to a multitude of real-world problems and, hence, a variety of computational techniques have been developed to efficiently locate it.
Glykeria Kyrou, Vasileios Charilogis, Ioannis G. Tsoulos   +2 more
doaj   +1 more source

The q-gradient method for global optimization

, 2013
The q-gradient is an extension of the classical gradient vector based on the concept of Jackson's derivative. Here we introduce a preliminary version of the q-gradient method for unconstrained global optimization. The main idea behind our approach is the
Galski, Roberto L., Ramos, Fernando M., Soterroni, Aline C.   +2 more
core   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Electrical Storm Optimization (ESO) Algorithm: Theoretical Foundations, Analysis, and Application to Engineering Problems

Machine Learning and Knowledge Extraction
The electrical storm optimization (ESO) algorithm, inspired by the dynamic nature of electrical storms, is a novel population-based metaheuristic that employs three dynamically adjusted parameters: field resistance, field intensity, and field ...
Manuel Soto Calvo, Han Soo Lee
doaj   +1 more source

Hole Filling for View Synthesis Using Depth Guided Global Optimization

IEEE Access, 2018
View synthesis is an effective way to generate multi-view contents from a limited number of views, and can be utilized for 2-D-to-3-D video conversion, multi-view video compression, and virtual reality. In the view synthesis techniques, depth-image-based
Guibo Luo, Yuesheng Zhu
doaj   +1 more source

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

FEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer, Philip Hinchliffe, Marko Hanževački, Christopher R. Bethel, Catherine L. Tooke, Marc W. Van der Kamp, Krisztina M. Papp‐Wallace, Robert A. Bonomo, Stuart Shapiro, Adrian J. Mulholland, James Spencer   +10 more
wiley   +1 more source

An Enhanced Tree-Seed Algorithm for Function Optimization and Production Optimization

Biomimetics
As the fields of engineering, energy, and geology become increasingly complex, decision makers face escalating challenges that require skilled solutions to meet practical production needs.
Qingan Zhou, Rong Dai, Guoxiao Zhou, Shenghui Ma, Shunshe Luo   +4 more
doaj   +1 more source

Global Optimality in Low-Rank Matrix Optimization [PDF]

IEEE Transactions on Signal Processing, 2017
This paper considers the minimization of a general objective function $f(X)$ over the set of rectangular $n\times m$ matrices that have rank at most $r$. To reduce the computational burden, we factorize the variable $X$ into a product of two smaller matrices and optimize over these two matrices instead of $X$. Despite the resulting nonconvexity, recent
Zhihui Zhu, Qiuwei Li, Gongguo Tang, Michael B. Wakin   +3 more
openaire   +3 more sources

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source