Results 71 to 80 of about 1,449,938 (284)
, 2018 In the article we present a general theory of augmented Lagrangian functions for cone constrained optimization problems that allows one to study almost all known augmented Lagrangians for cone constrained programs within a unified framework. We develop a
Dolgopolik, M. V.
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Thermodynamics of Global Optimization
Physical Review Letters, 1998 Theoretical design of global optimization algorithms can profitably utilize recent statistical mechanical treatments of potential energy surfaces (PES's). Here we analyze a particular method to explain its success in locating global minima on surfaces with a multiple-funnel structure, where trapping in local minima with different morphologies is ...
Doye, J, Wales, D
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The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Fast Task Scheduling With Model Predictive Control Integrating a Priority-Based Heuristic
IEEE AccessThis paper presents a scalable Model Predictive Control (MPC) algorithm for task scheduling and real time re-scheduling. The use case motivating the work is given by the problem of managing the integration activities involved in the final assembly of the
Francesco Liberati +3 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
DIFFERENTIAL EVOLUTION WITH COMPETITIVE SETTING OF CONTROL PARAMETERS
TASK Quarterly, 2007 This paper is focused on the adaptation of control parameters in differential evolution. Competition of various control parameter settings was proposed in order to ensure self-adaptation of parameter values in the search process.
JOSEF TVRD´IK
doaj
Simulator-based training of generative neural networks for the inverse design of metasurfaces
Nanophotonics, 2019 Metasurfaces are subwavelength-structured artificial media that can shape and localize electromagnetic waves in unique ways. The inverse design of these devices is a non-convex optimization problem in a high dimensional space, making global optimization ...
Jiang Jiaqi, Fan Jonathan A.
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Global Optimization Using Space Filling Curves
Advances in Electrical and Electronic Engineering, 2017 The existence of space filling curves opens the way to reducing multivariate optimization problems to the minimization of univariate functions. In this paper, we analyze the Hoelder continuity of space filling curves and exploit this property in the ...
Michaela Bailova +2 more
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GLOBAL OPTIMIZATION METHODS [PDF]
Training a neural network is a difficult optimization problem because of numerous local minimums. Many global search algorithms have been used to train neural networks. However, local search algorithms are more efficient with computational resources, and
Brorsen, B. Wade, Hamm, Lonnie
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