Results 91 to 100 of about 892,070 (301)

The public goods hypothesis for the evolution of life on Earth

open access: yesBiology Direct, 2011
It is becoming increasingly difficult to reconcile the observed extent of horizontal gene transfers with the central metaphor of a great tree uniting all evolving entities on the planet. In this manuscript we describe the Public Goods Hypothesis and show
Bapteste Eric   +3 more
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Globalization and Biodiversity Conservation Problems: Polycentric REDD+ Solutions

open access: yesLand, 2019
Protected areas are considered the cornerstone of biodiversity conservation, but face multiple problems in delivering this core objective. The growing trend of framing biodiversity and protected area values in terms of ecosystem services and human well ...
Mwangi Githiru, Josephine W. Njambuya
doaj   +1 more source

Financing the Provision of Global Public Goods [PDF]

open access: yes
global public goods, international organizations, aid, externality, Global Environment ...
Anand, P.B.
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Patenting the Sun? Possible Exclusion of SRM Technologies from Patenting and Risk Regulation

open access: yesEuropean Journal of Risk Regulation
In an interview with Jonas Salk, the inventor of the first polio vaccine, when asked whether he owned the patents for the vaccine, Salk replied with a rhetorical question: “Could you patent the sun?” Decades later, patents about the Sun indeed emerged as
Wenting Cheng
doaj   +1 more source

Impact of Risk and Uncertainty in the Provision of Local and Global Environmental Goods : An Experimental Analysis [PDF]

open access: yes
Uncertainties and risks in the decision making process are abundant in the area of environmental economics, irrespective of whether the problems being discussed are local or global.
Lata Gangadharan, Veronika Nemes
core  

Marketing in the Public Sector [PDF]

open access: yes, 2010
{Excerpt} The public sector is the part of economic life, not in private ownership, that deals with the production, delivery, and allocation of basic public goods and services at global, regional, national, or local levels.
Serrat, Olivier
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Life After Kyoto: Alternative Approaches to Global Warming [PDF]

open access: yes
This study reviews different approaches to the political and economic control of global public goods like global warming. It compares quantity-oriented control mechanisms like the Kyoto Protocol with price-type control mechanisms such as internationally ...
William Nordhaus
core  

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