Results 91 to 100 of about 894,820 (296)
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Globalization and public administration: a complex relationship [PDF]
The paper examines the relationship between globalization and public administration through economic theory principles and an example. Starting from the consideration of early concerns about globalization, it argues that although the size of government ...
Elisabetta Croci Angelini
core +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
The public goods hypothesis for the evolution of life on Earth
Biology Direct, 2011 It is becoming increasingly difficult to reconcile the observed extent of horizontal gene transfers with the central metaphor of a great tree uniting all evolving entities on the planet. In this manuscript we describe the Public Goods Hypothesis and show
Bapteste Eric +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
Patenting the Sun? Possible Exclusion of SRM Technologies from Patenting and Risk Regulation
European Journal of Risk RegulationIn an interview with Jonas Salk, the inventor of the first polio vaccine, when asked whether he owned the patents for the vaccine, Salk replied with a rhetorical question: “Could you patent the sun?” Decades later, patents about the Sun indeed emerged as
Wenting Cheng
doaj +1 more source
Less government intervention in biodiversity management: risks and opportunities [PDF]
, 2012 n a changing global environment, with increasing pressure on ecosystem goods and services, biodiversity conservation is likely to become increasingly important.
Butler, James R. A. +3 more
core +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Globalization and Biodiversity Conservation Problems: Polycentric REDD+ Solutions
Land, 2019 Protected areas are considered the cornerstone of biodiversity conservation, but face multiple problems in delivering this core objective. The growing trend of framing biodiversity and protected area values in terms of ecosystem services and human well ...
Mwangi Githiru, Josephine W. Njambuya
doaj +1 more source
How can donors help build global public goods in health ? [PDF]
Aid to developing countries has largely neglected the population-wide health services that are core to communicable disease control in the developed world.
Das Gupta, Monica, Gostin, Lawrence
core