Results 71 to 80 of about 892,070 (301)

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Reframing aid in a world where the poor live in emerging economies

open access: yesRevue Internationale de Politique de Développement, 2012
This special issue of International Development Policy analyses the major shifts affecting traditional development assistance, particularly with regard to global public policy and the emerging economies.
Gilles Carbonnier, Andy Sumner
doaj   +1 more source

Aid Financing of Global Public Goods: an Update [PDF]

open access: yes
The paper compares different aggregates of aid financed global public goods and detects the presence, for the period 1995-2006, of the substitution effect between these aggregates and traditional aid that was found by former studies for earlier periods ...
Cepparulo, Alessandra, Giuriato, Luisa
core   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Migrants and mafia as global public goods [PDF]

open access: yes
Global public goods, differently from what it might be thought, are quite common in the real world. This work suggests that both the governments' struggle against Mafia and the prevention of immigration can be regarded as global public goods. We assume a
Fossati, Amedeo, Montefiori, Marcello
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Financing the Provision of Global Public Goods [PDF]

open access: yesThe World Economy, 2004
This paper examines the concept of global public goods (GPGs) and in that context explores the extent of aid (ODA) presently being diverted to GPG provision and whether such diversion skews aid‐flows towards some recipients. These are examined on the basis of OECD data for the late 1990s.
openaire   +3 more sources

The Effects of Group Interaction in a Public Goods Experiment With Two Exchanges [PDF]

open access: yes
Consumers can often allocate resources to the provision of local public goods and to the provision of global public goods. This paper reports a public goods experiment in which participants allocated tokens to a local exchange with a relatively high ...
Yoav Wachsman
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

KÜRESEL KAMUSAL MALLAR VE FİNANSMANI GLOBAL PUBLIC GOODS AND FINANCING

open access: yesSelçuk Üniversitesi Sosyal Bilimler Meslek Yüksekokulu Dergisi, 2014
Küresel kamusal mallar genelde önemsenmeyen ancak aynı derecede önemli bir kavramdır. Yaşamın devamı, iklim değişikliğinin, savaşların, hastalıkların engellenmesi, bütünleşmenin, serbest ticaretin insan haklarının gelişmesi için gerekli her türlü mal ve ...
Hasan Sencer Peker, İsa Altınışık
doaj  

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