Results 121 to 130 of about 2,416,289 (329)

Globalisation, domestic inflation and global output gaps: Evidence from the euro area [PDF]

This paper tests whether the proposition that globalisation has led to greater sensitivity of domestic inflation to the global output gap (the “global output gap hypothesis”) holds for the euro area.
Calza, Alessandro
core  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Estimating the relative importance of epidemiological and behavioural parameters for epidemic mpox transmission: a modelling study

BMC Medicine
Background Many European countries experienced outbreaks of mpox in 2022, and there was an mpox outbreak in 2023 in the Democratic Republic of Congo. There were many apparent differences between these outbreaks and previous outbreaks of mpox; the recent ...
Madhav Chaturvedi, Isti Rodiah, Mirjam Kretzschmar, Stefan Scholz, Berit Lange, André Karch, Veronika K. Jaeger   +6 more
doaj   +1 more source

Local and global sensitivity analysis for railway upgrading between hydrogen fuel cell and electrification

High-Speed Railway
In the field of rail transit, the UK Department of Transport stated that it will realize a comprehensive transformation of UK railways by 2050, abandoning traditional diesel trains and upgrading them to new environmentally friendly trains.
Yizhe Zhang, Zhongbei Tian, Kangrui Jiang, Stuart Hillmansen, Clive Roberts   +4 more
doaj   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Mixed-Variable Global Sensitivity Analysis For Knowledge Discovery And Efficient Combinatorial Materials Design [PDF]

, 2023
Yigitcan Comlek, Liwei Wang, Wei Chen
openalex   +1 more source

National economic policy simulations with global interdependencies : a sensitivity analysis for Germany [PDF]

"Policy simulations for national economies with econometric models in general are done using a stand alone national model with exogenous export values and import prices. In a globalised world such an exercise is critical, since the policy in question may
Lutz, Christian, Meyer, Bernd, Schnur, Peter, Zika, Gerd   +3 more
core  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Computational Method for Global Sensitivity Analysis of Reactor Neutronic Parameters

Science and Technology of Nuclear Installations, 2012
The variance-based global sensitivity analysis technique is robust, has a wide range of applicability, and provides accurate sensitivity information for most models. However, it requires input variables to be statistically independent.
Bolade A. Adetula, Pavel M. Bokov
doaj   +1 more source

Applying a Global Sensitivity Analysis Workflow to Improve the Computational Efficiencies in Physiologically-Based Pharmacokinetic Modeling [PDF]

, 2018
Nan‐Hung Hsieh, Brad Reisfeld, Frédéric Y. Bois, Weihsueh A. Chiu   +3 more
openalex   +1 more source