Results 91 to 100 of about 3,715,226 (283)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Global existence and blow-up of solutions to pseudo-parabolic equation for Baouendi-Grushin operator

open access: yesOpen Mathematics
In this note, we study a global existence and blow-up of the positive solutions to the initial-boundary value problem of the nonlinear pseudo-parabolic equation for the Baouendi-Grushin operator.
Dukenbayeva Aishabibi
doaj   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Pullback attractors for non-autonomous parabolic equations involving Grushin operators

open access: yesElectronic Journal of Differential Equations, 2010
Using the asymptotic a priori estimate method, we prove the existence of pullback attractors for a non-autonomous semilinear degenerate parabolic equation involving the Grushin operator in a bounded domain.
Cung The Anh
doaj  

Global asymptotic behavior of solutions to quasilinear schrodinger equations

open access: yesElectronic Journal of Differential Equations, 2020
We are concerned with the existence and blowup of solutions for a class of quasilinear Schrodinger equations. In particular, we examine the combined effect of local type nonlinearity and Hartree type ones, and depending upon different parameter ...
Lin Zhang, Xianfa Song
doaj  

Ordinary differential equations and descriptive set theory: uniqueness and globality of solutions of Cauchy problems in one dimension

open access: yes, 1996
We study some natural sets arising in the theory of ordinary differential equations in one variable from the point of view of descriptive set theory and in particular classify them within the Borel hierarchy.
Andretta, Alessandro, Marcone, Alberto
core  

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Nonlinear convection in reaction-diffusion equations under dynamical boundary conditions

open access: yesElectronic Journal of Differential Equations, 2013
We study the blow-up phenomena for positive solutions of nonlinear reaction-diffusion equations including a nonlinear convection term $partial_t u = Delta u - g(u) cdot abla u + f(u)$ in a bounded domain of $mathbb{R}^N$ under the dissipative ...
Gaelle Pincet Mailly   +1 more
doaj  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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