Results 61 to 70 of about 3,715,226 (283)

Boundedness and global solvability for a chemotaxis-haptotaxis model with p-Laplacian diffusion

open access: yesElectronic Journal of Differential Equations, 2020
We consider a chemotaxis-haptotaxis system with $p$-Laplacian diffusion in three dimensional bounded domains. It is asserted that for any p>2, under the appropriate assumptions, the chemotaxis-haptotaxis system admits a global bounded weak ...
Changchun Liu, Pingping Li
doaj  

Predicting the Future Burden of Renal Replacement Therapy in Türkiye Using National Registry Data and Comparative Modeling Approaches

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic kidney disease is a growing public health problem worldwide, and the number of patients requiring renal replacement therapy is steadily increasing. Türkiye has experienced a similar rise in both the incidence and prevalence of renal replacement therapy over the past decades; however, national‐level projections of future ...
Arzu Akgül   +2 more
wiley   +1 more source

Existence of global solutions for systems of second-order differential equations with p-Laplacian

open access: yesElectronic Journal of Differential Equations, 2007
We obtain sufficient conditions for the existence of global solutions for the systems of differential equations $$ ig(A(t)Phi_p(y')ig)' + B(t)g(y') + R(t)f(y) = e(t), $$ where $Phi_p(y')$ is the multidimensional p-Laplacian.
Eva Pekarkova, Milan Medved
doaj  

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Biosimilars – Global issues, national solutions

open access: yesBiologicals, 2011
Biotechnology derived medicinal products are presently the best characterized biologicals with considerable production and clinical experience, and have revolutionized the treatment of some of the most difficult-to-treat diseases, prolonging and improving the quality of life and patient care.
Knezevic, Ivana, Griffiths, Elwyn
openaire   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Blowup and existence of global solutions to nonlinear parabolic equations with degenerate diffusion

open access: yesElectronic Journal of Differential Equations, 2013
In this article, we consider the degenerate parabolic equation $$ u_t-\hbox{div}(|\nabla u|^{p-2}\nabla u) =\lambda u^m+\mu|\nabla u|^q $$ on a smoothly bounded domain $\Omega\subseteq\mathbb{R}^N\; (N\geq2)$, with homogeneous Dirichlet boundary ...
Zhengce Zhang, Yan Li
doaj  

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

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