Results 221 to 230 of about 82,601 (269)

A model of globin evolution

open access: yesGene, 2007
Putative globins have been identified in 426 bacterial, 32 Archaeal and 67 eukaryote genomes. Among these sequences are the hitherto unsuspected presence of single domain sensor globins within Bacteria, Fungi, and a Euryarchaeote. Bayesian phylogenetic trees suggest that their occurrence in the latter two groups could be the result of lateral gene ...
Serge N Vinogradov   +2 more
exaly   +5 more sources
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Globin X: A highly stable intrinsically hexacoordinate globin

Journal of Inorganic Biochemistry, 2022
Several novel members of the vertebrate globin family were recently discovered with unique structural features that are not found in traditional penta-coordinate globins. Here we combine structural tools to better understand and recognize molecular determinants that contribute to the stability of hexacoordinate globin X (GbX) from Danio rerio ...
Rifat, Farhana   +8 more
openaire   +2 more sources

Joining the loops: β‐Globin gene regulation

open access: yesIUBMB Life, 2008
The mammalian beta-globin locus is a multigene locus containing several globin genes and a number of regulatory elements. During development, the expression of the genes changes in a process called "switching." The most important regulatory element in ...
Daan Noordermeer, Wouter De Laat
exaly   +3 more sources

A globin for the brain

The FASEB Journal, 2006
The discovery that a myoglobin‐like hemeprotein (called neuroglobin) is expressed in our brain raised considerable curiosity from the standpoints of biochemistry and pathophysiology alike. Neuroglobin is involved in neuroprotection from damage due to hypoxia or ischemia in vitro and
BRUNORI, Maurizio, VALLONE, Beatrice
openaire   +4 more sources

Microbial globins

2003
Globins are an ancient and diverse superfamily of proteins. The globins of microorganisms were relatively ignored for many decades after their discovery by Warburg in the 1930s and rediscovery by Keilin in the 1950s. The relatively recent focus on them has been fuelled by recognition of their structural diversity and fine-tuning to fulfill (probably ...
Guanghui, Wu   +2 more
openaire   +2 more sources

The Globins of Campylobacter jejuni

2013
Campylobacter jejuni is a zoonotic Gram-negative bacterial pathogen that is exposed to reactive nitrogen species, such as nitric oxide, from a variety of sources. To combat the toxic effects of this nitrosative stress, C. jejuni upregulates a small regulon under the control of the transcriptional activator NssR, which positively regulates the ...
Mariana, Tinajero-Trejo, Mark, Shepherd
openaire   +2 more sources

The Globins of Cyanobacteria and Algae

2013
Approximately, 20 years ago, a haemoglobin gene was identified within the genome of the cyanobacterium Nostoc commune. Haemoglobins have now been confirmed in multiple species of photosynthetic microbes beyond N. commune, and the diversity of these proteins has recently come under increased scrutiny.
Eric A, Johnson, Juliette T J, Lecomte
openaire   +2 more sources

Molecular weight determinations on the α-globin and β-globin mRNAs

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1976
The globin mRNAs containing between 30 and 40 polyadenylate residues can be separated from thos mRNAs containing longer poly(A) regions by Millipore filter binding. The molecular weights of the alpha-and beta-globin mRNAs containing this size class of poly(A) have beed determined by lectrophoresis on 3.7% polyacrylamide gels in the presence of 99 ...
M R, Morrison, J B, Lingrel
openaire   +2 more sources

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