Results 231 to 240 of about 74,517 (259)
Dual α-globin-truncated erythropoietin receptor knockin restores hemoglobin production in α-thalassemia-derived erythroid cells. [PDF]
Cell RepChu SN +24 more
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TFII-I/GTF2I regulates globin gene expression and stress response in erythroid cells. [PDF]
J Biol ChemNar R +5 more
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Preclinical efficacy of a modified gamma-globin lentivirus gene therapy in Berkeley sickle cell anemia mice and human xenograft models. [PDF]
Mol Ther Methods Clin DevShrestha A +8 more
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Hemoglobin S Promotes Glycemic Dysregulation in a Mouse Model of Human Sickle Cell Disease.
EndocrinologyZapater JL +4 more
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Globin X: A highly stable intrinsically hexacoordinate globin
Journal of Inorganic Biochemistry, 2022Several novel members of the vertebrate globin family were recently discovered with unique structural features that are not found in traditional penta-coordinate globins. Here we combine structural tools to better understand and recognize molecular determinants that contribute to the stability of hexacoordinate globin X (GbX) from Danio rerio ...
Rifat, Farhana +8 more
openaire +2 more sources
The FASEB Journal, 2006
The discovery that a myoglobin-like hemeprotein (called neuroglobin) is expressed in our brain raised considerable curiosity from the standpoints of biochemistry and pathophysiology alike. Neuroglobin is involved in neuroprotection from damage due to hypoxia or ischemia in vitro and in vivo; overexpression of neuroglobin ameliorates the recovery from ...
BRUNORI, Maurizio, VALLONE, Beatrice
openaire +5 more sources
The discovery that a myoglobin-like hemeprotein (called neuroglobin) is expressed in our brain raised considerable curiosity from the standpoints of biochemistry and pathophysiology alike. Neuroglobin is involved in neuroprotection from damage due to hypoxia or ischemia in vitro and in vivo; overexpression of neuroglobin ameliorates the recovery from ...
BRUNORI, Maurizio, VALLONE, Beatrice
openaire +5 more sources
Gene, 2007
Putative globins have been identified in 426 bacterial, 32 Archaeal and 67 eukaryote genomes. Among these sequences are the hitherto unsuspected presence of single domain sensor globins within Bacteria, Fungi, and a Euryarchaeote. Bayesian phylogenetic trees suggest that their occurrence in the latter two groups could be the result of lateral gene ...
Vinogradov, Serge N. +6 more
openaire +4 more sources
Putative globins have been identified in 426 bacterial, 32 Archaeal and 67 eukaryote genomes. Among these sequences are the hitherto unsuspected presence of single domain sensor globins within Bacteria, Fungi, and a Euryarchaeote. Bayesian phylogenetic trees suggest that their occurrence in the latter two groups could be the result of lateral gene ...
Vinogradov, Serge N. +6 more
openaire +4 more sources
2003
Globins are an ancient and diverse superfamily of proteins. The globins of microorganisms were relatively ignored for many decades after their discovery by Warburg in the 1930s and rediscovery by Keilin in the 1950s. The relatively recent focus on them has been fuelled by recognition of their structural diversity and fine-tuning to fulfill (probably ...
Guanghui, Wu +2 more
openaire +2 more sources
Globins are an ancient and diverse superfamily of proteins. The globins of microorganisms were relatively ignored for many decades after their discovery by Warburg in the 1930s and rediscovery by Keilin in the 1950s. The relatively recent focus on them has been fuelled by recognition of their structural diversity and fine-tuning to fulfill (probably ...
Guanghui, Wu +2 more
openaire +2 more sources