Results 61 to 70 of about 13,059 (104)

COUP-TFII regulates hemoglobin switching by activating the BCL11A-XL repressor LIN28B and directly binding δ and β globin promoters in fetal <i>versus</i> adult erythroid cells. [PDF]

Haematologica
Frigo C, Pastori V, Zambanini G, Fabiano M, Ahmed S, Citterio E, Cantù C, Ronchi AE.   +7 more
europepmc   +1 more source

Comparative analysis of CRISPR-Cas9, lentiviral transduction, and base editing for sickle cell disease in a murine model. [PDF]

Blood Adv
Butt H, Sathish S, London E, Le A, Li Q, Gudmundsdottir B, Lee DY, Burke EV, Yates BP, Liu DR, Hsieh M, Leonard A, Eaton WA, Uchida N, Pierciey FJ, Newby GA, Tisdale JF, Demirci S.   +17 more
europepmc   +1 more source

Inhibition of XPO1 by selinexor enhances terminal erythroid maturation through modulation of HSP70 trafficking in severe β0-thalassemia/HbE. [PDF]

PLoS One
Khamphikham P, Tantiworawit A, Anuchapreeda S.   +2 more
europepmc   +1 more source

ATRX loss couples genome instability at a G-rich repeat to dysregulation of human alpha-globin expression. [PDF]

Nat Commun
Shen Y, Gupta K, Tan-Wong SM, Wen S, Fisher CA, Tamon L, Proudfoot NJ, Gibbons RJ, Higgs DR.   +8 more
europepmc   +1 more source

VaxLab: integrated platform for rapid multistrategy mRNA vaccine design. [PDF]

Exp Mol Med
Kim J, Han Y, Kwon CY, Chang H.
europepmc   +1 more source

m⁶A mRNA Methylation in Hematopoiesis: The Importance of Writing, Erasing, and Reading. [PDF]

Cells
Vasilopoulou AG, Kalafati E, Drakopoulou E, Anagnou NP.   +3 more
europepmc   +1 more source

High-titer modular retroviral vectors enabled by an antisense cassette design preventing dsRNA formation during virus production. [PDF]

Mol Ther Adv
Vuillefroy de Silly R, Reichenbach P, Irving M.   +2 more
europepmc   +1 more source

Genetic polymorphism of SNPs rs9399137 and rs4895441in HBS1L-MYB and SNP rs766432 in BCL11A among β-thalassemia Egyptian patients. [PDF]

BMC Genom Data
Abdelrahman AA, Talaat RM, El-Halfawy IA, Alalwi MR, Rizk DMY.   +4 more
europepmc   +1 more source

G2B: an optimized lentiviral vector with enhanced titer and β-globin expression for improved β-thalassemia gene therapy. [PDF]

Blood Sci
Gao ZY, Yang ZX, Deng DH, Zhang F, Yu B, Zhang YY, Lv X, Nakamura Y, Gong A, Cheng T, Zhang JP, Zhang XB.   +11 more
europepmc   +1 more source

mRNA-based immunotherapy platform targeting endometrial cancer. [PDF]

J Transl Med
Freyberg M, Dierks M, Nass N, George C, Geffken M, Ignatov A, Kalinski T, Ignatova Z.   +7 more
europepmc   +1 more source