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The Globins of Cyanobacteria and Algae

2013
Approximately, 20 years ago, a haemoglobin gene was identified within the genome of the cyanobacterium Nostoc commune. Haemoglobins have now been confirmed in multiple species of photosynthetic microbes beyond N. commune, and the diversity of these proteins has recently come under increased scrutiny.
Juliette T. J. Lecomte, Eric A. Johnson
openaire   +2 more sources

Microbial Eukaryote Globins

2013
A bioinformatics survey of about 120 protist and 240 fungal genomes and transcriptomes revealed a broad array of globins, representing five of the eight subfamilies identified in bacteria. Most conspicuous is the absence of protoglobins and globin-coupled sensors, except for a two-domain globin in Leishmanias, that comprises a nucleotidyl cyclase ...
Serge N. Vinogradov   +5 more
openaire   +3 more sources

Activation of the δ-Globin Gene by the β-Globin Gene CACCC Motif

Blood Cells, Molecules, and Diseases, 1999
The promoter region of adult beta globin genes in humans and other mammals contains conserved regions of pivotal importance for their regulated tissue specific expression. These include the CACCC and CAAT motifs. The CACCC motif is duplicated in humans and other mammals.
M. S. RISTALDI   +5 more
openaire   +4 more sources

Increase in globin chains and globin mRNA in erythroleukemia cells in response to hemin

Archives of Biochemistry and Biophysics, 1977
Abstract Addition of 50 μ m hemin to mouse erythroleukemia cells cultured in 0.5% dimethyl-sulfoxide (DMSO) resulted in >10-fold stimulation of globin chain synthesis as a percentage of acid precipitable protein. In cultures fully induced with 1.5% DMSO, addition of 15 m m 3-amino-1,2,4-triazole (AT), an inhibitor of heme synthesis, reduced globin ...
Betty J. Dabney, Arthur L. Beaudet
openaire   +2 more sources

Nutritive Value of Globin-Amino Acid and Complementary Globin-Cereal Mixtures

The Journal of Nutrition, 1980
Protein efficiency ratios (PER) were determined using male weanling rats fed diets containing bovine globin alone and with wheat and corn gluten. Simultaneous equations and graphical methods were devised for selecting combinations of globin and cereal proteins to provide optimal and suboptimal profiles of limiting amino acids.
Wendell A. Landmann   +2 more
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Ratios of α-to β-globin mRNA and regulation of globin synthesis in reticulocytes

Nature, 1977
THE genomes of several mammalian species contain at least two α globin loci and a single β globin locus so that the ratio of α- to β-globin genes is 2 : 1 or more1–3. Despite this difference in number of genes, reticulocytes from these species synthesise equal numbers of α- and β-globin chains indicating that compensatory regulation must occur ...
J. A. Phillips   +2 more
openaire   +3 more sources

Globin Interactions with Lipids and Membranes

2008
Many bacterial globins have been demonstrated to interact with membrane lipids, and several hypotheses in support of a functional role for membrane localization have been set forth. Bacterial globins have been suggested to facilitate oxygen diffusion to terminal oxidases, to protect oxidases from nitric oxide or eventually to preserve the integrity of ...
DI GIULIO, Antonio, BONAMORE A.
openaire   +4 more sources

Control of catalysis in globin coupled adenylate cyclase by a globin-B domain

Archives of Biochemistry and Biophysics, 2015
The globin coupled heme containing adenylate cyclase from Leishmania major (HemAC-Lm) has two globin domains (globin-A and globin-B). Globin-B domain (210-360 amino acids) may guide the interaction between globin-A and adenylate cyclase domains for the regulation of catalysis.
Subrata Adak   +4 more
openaire   +3 more sources

ON GLOBIN AND DENATURED GLOBIN

Australian Journal of Experimental Biology and Medical Science, 1928
Mavis Freeman, Henry Francis Holden
openaire   +2 more sources

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