Results 151 to 160 of about 45,771 (276)
Causative Human Papillomavirus (HPV) Genotypes of Anal Cancers in Australian Cisgender Women
ABSTRACT Anal cancer, caused by persistent infection with oncogenic human papillomavirus (HPV), is rare in the general population. However, certain groups, such as men who have sex with men living with HIV, are at much higher risk, and research into the etiology and pathogenesis of the disease has focused on this group.
Clare E. F. Dyer +8 more
wiley +1 more source
ABSTRACT Fragilariopsis cylindrus is a key diatom in the Southern Ocean, where low iron and manganese availability constrain primary production and biogeochemical activity. The molecular mechanisms used by polar diatoms, including F. cylindrus, to cope with trace metal limitations remain largely unexplored.
Loay J. Jabre +3 more
wiley +1 more source
ABSTRACT Objective To evaluate the analytical suitability of different storage and laboratory processes of self‐samples for an HPV assay. Design Prospective matched study. Setting Royal London Hospital Colposcopy Clinic. Population One hundred seventy seven patients aged 25–65 years referred to colposcopy due to their screening results (abnormal ...
Kim Chu +12 more
wiley +1 more source
Cellular senescence and mitochondrial dysfunction disrupt adipose tissue homeostasis during aging, but mechanisms remain unclear. HDAC9 expression increases with age in mouse adipose tissue and Hdac9 knockout mice showed reduced fat mass, senescence markers, and enhanced mitochondrial gene expression, respiration, and thiosulfate sulfurtransferase (Tst)
Brandee Goo +15 more
wiley +1 more source
Whole Blood Transcriptomic Analysis of Sickle Cell Trait
ABSTRACT Sickle cell trait (SCT) is the heterozygous carrier state for the HBB missense variant which causes sickle cell disease (SCD). SCT has been associated with increased risk of venous thromboembolism and chronic kidney disease as well as alterations in clinical laboratory parameters. To investigate differential gene expression in SCT, we used RNA
Mari Johnson +12 more
wiley +1 more source
Evolution of Single-Domain Globins in Hydrothermal Vent Scale-Worms
J. Projecto-Garcia +6 more
semanticscholar +1 more source
Abstract We developed a noninvasive approach to measure vascular responses to sympathetic stimuli. We hypothesized that standing, handgrip exercise, or cold exposure would raise blood pressure (BP) and lower renal vascular conductance (RVC). BP was recorded continuously and renal arterial velocity was measured using renal Doppler ultrasound.
Mohamed H. Ibrahim +7 more
wiley +1 more source
Probing the Cancer Mutational Landscape of KMT2 Regulatory Subunits
Pipeline to characterize the KMT2 cancer mutational landscape starts with querying genomic databases (top left) for mutations mapping to ASH2L, RbBP5, WDR5, and DPY‐30. Subsequent steps include the expression of these mutants in cell (bottom left), their systemic purification and biochemical characterization using isothermal titration calorimetry ...
Sabrina Grégoire +9 more
wiley +1 more source
Diversity and conservation of interactions for binding heme in b-type heme proteins [PDF]
Marles-Wright, Jon +3 more
core +1 more source

