Results 131 to 140 of about 9,131 (243)

Microfluidic Profiling of an Immune Cell‐Associated Extracellular Vesicle Signature for Active Tuberculosis Diagnosis and Treatment Monitoring

Journal of Extracellular Vesicles, Volume 15, Issue 11, November 2026.
Integrating microfluidic parallel detection with an innate immune extracellular vesicle signature enables rapid active tuberculosis diagnosis from 10 µL of plasma in 30 minutes, effectively discriminating non‐tuberculous respiratory diseases and monitoring treatment response.
Eun Ju Lee, Cheng Nie, Sunyoung Park, Yun‐Jeong Kang, Minji Kang, Jake Whang, Go‐Eun Choi, Hyejon Lee, San‐Nae Cho, Kyung‐A Hyun, Sunghyun Kim, Hyo‐Il Jung, Jungho Kim   +12 more
wiley   +1 more source

Photometallobiocatalytic Asymmetric Radical‐Mediated Cross‐Coupling of Organotrifluoroborate Salts and Pyridotriazoles

Angewandte Chemie, Volume 138, Issue 42, 12 October 2026.
An enantioselective photometallobiocatalytic cross‐coupling of pyridotriazoles and secondary alkyltrifluoroborate salts is developed. Cooperative catalysis using eosin B and an engineered protoglobin combines visible‐light‐mediated radical generation with enzymatic metal carbenoid activation, affording valuable N‐heterocyclic products in excellent ...
Huanan Wang, Binh Khanh Mai, Xingjie Zhang, Chongtao Li, Peng Liu, Yang Yang   +5 more
wiley   +2 more sources

Ligand binding in globins of Caenorhabditis elegans and Methanosarcina acetivorans : from over-expression to spectroscopic characterization

, 2023
: This thesis comprises studies on heme-containing proteins, including globin 33 (GLB-33) and GLB-3 from Caenorhabditis elegans (C. elegans), and the Protoglobin of Methanosarcina acetivorans (MaPgb), and their interactions with nitrite and nitric oxide (
Van Brempt, Niels
core   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, Volume 46, Issue 6, Page 1574-1602, November 2026.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

Bayesian phylogenetic tree of fungal and bacterial T1 globins.

, 2012
Bayesian tree based on a T-COFFEE 9.01 alignment of 2 fungal (red and black arrows), 70 bacterial (blue), 4 euryarchaeote (purple) and 10 chlorophyte (green) T1 globins, using 2 Physcomitrella nsHbs as outgroup.
Serge N. Vinogradov (181327), Andy Vierstraete (40054), Sylvia Dewilde (40053), Luc Moens (40055), David Hoogewijs (40051)   +4 more
core   +1 more source

Determination of ligand pathways in globins apolar tunnels versus polar gates

, 2012
: Although molecular dynamics simulations suggest multiple interior pathways for O-2 entry into and exit from globins, most experiments indicate well defined single pathways.
M. Bolognesi, Dewilde, Sylvia, Soman, Jayashree, M. Nardini, Olson, John S., Blouin G. C., Olson J. S., Singleton, Eileen W., Pesce, Alessandra, Dewilde S., E. W. Singleton, Singleton E. W., Bolognesi M., Salter M. D., G. C. Blouin, Bolognesi, Martino, Nardini M., L. Moens, Blouin, George C., J. S. Olson, A. Pesce, Moens L., M. D. Salter, Nardini, Marco, Singleton, Eileen Willey, J. Soman, S. Dewilde, Soman J., Salter, Mallory D., Moens, Luc   +29 more
core   +1 more source

The role of iron in normal and impaired testicular function

Andrology, Volume 14, Issue 8, Page 2373-2387, November 2026.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer, Esther G. Meyron‐Holtz, Andreas Meinhardt   +2 more
wiley   +1 more source

A matrix-assisted laser desorption/ionization mass spectrometry study of thenon-enzymatic glycation products of human globins in diabetes

, 2005
The molecular species present in globins from healthy and diabetic subjects with and without chronic complications have been analyzed by matrix-assisted laser desorption/ionization mass spectrometry.
LAPOLLA, ANNUNZIATA, TUBARO M., ARICO', CONCETTA NADIA, FEDELE, DOMENICO, SERAGLIA R., VEGLIARDI S., TRALDI P., REITANO R., RAGAZZI, EUGENIO   +8 more
core   +1 more source

Nuclear Wrinkles Result From Geometric Adaptations to Cellular and Nuclear Morphological Changes in Epithelial Cells

Genes to Cells, Volume 31, Issue 6, November 2026.
Changes in cell geometry caused by increased cell density, F‐actin disruption, or trypsinization promote nuclear rounding and nuclear wrinkle (NW) formation. NWs arise through passive redistribution of excess nuclear surface area and are reversible, without detectable DNA damage, stress‐associated histone H3 Ser10 phosphorylation, or global nuclear ...
Le Minh Khoa, Yohei Kono, Takeshi Shimi, Hiroshi Kimura   +3 more
wiley   +1 more source

The Maternal Blood Transcriptome Reflects Molecular Signatures Associated With Large Offspring Syndrome and Other Adverse Pregnancy Outcomes in Cattle

The FASEB Journal, Volume 40, Issue 20, 31 October 2026.
Blood samples from pregnant heifers carrying in vitro‐produced embryos were analyzed for RNA‐sequencing to test whether maternal blood transcriptome could be predictive of large offspring syndrome, stillbirth, and abortion compared with controls.
Tatiane S. Maia, Maria B. Rabaglino, Rebecca Krisher, Paula Rodriguez‐Villamil, Jeniffer Pamela J. Laguna, Jeniffer F. Escoto, Yanping Zhang, Abigail J. Sproull, Peter J. Hansen   +8 more
wiley   +1 more source