Results 111 to 120 of about 8,559 (239)
European Journal of Haematology, EarlyView.ABSTRACT Background Sickle cell disease (SCD) is a chronic and life‐limiting hemoglobin and systemic vascular disease. While over 1000 people have undergone hematopoietic cell transplantation (HCT) over the last 40 years, long‐term disease‐specific and health‐related quality of life data are lacking.
Gregory M. T. Guilcher +20 more
wiley +1 more source
F1000Research, 2015 Globins (Glbs) are proteins widely distributed in organisms. Three evolutionary families have been identified in Glbs: the M, S and T Glb families. The M Glbs include flavohemoglobins (fHbs) and single-domain Glbs (SDgbs); the S Glbs include globin ...
Reinier Gesto-Borroto +2 more
doaj +1 more source
PEG400 regulates Falcipain 2 activity through an allosteric mechanism
The FEBS Journal, EarlyView.Falcipain‐2 can potentially be leveraged as a drug target due to its critical role as a haemoglobinase during the intra‐erythrocytic stage of Plasmodium falciparum. Here, we investigate the regulation of the proteolytic and haemoglobinase activity of falcipain‐2 in the presence of polyethylene glycol.
Bikram Nath +2 more
wiley +1 more source
, 2013 Evolution allowed Antarctic microorganisms to grow successfully under extreme conditions (low temperature and high O-2 content), through a variety of structural and physiological adjustments in their genomes and development of programmed responses to ...
Giordano D +7 more
core +1 more source
Computational investigation of conformational and spectroscopic substates in neuroglobin [PDF]
, 2011 The family of globins has a strong significance in the history of protein research. Their abundance, spread in nature, and evolutionary diversity are crucial factors for a wide range of approved and suggested physiological functions taking place in ...
Lutz, Stephan Alexander
core +1 more source
Arsenite methyltransferase 3 is required for mitochondrial function and hepatic lipid metabolism
The FEBS Journal, EarlyView.AS3MT is a protein that helps the body process arsenic, a naturally occurring toxin found in water and soil. We discovered it also helps cells make and use energy properly. Without AS3MT, cells' mitochondria do not work well, leading to fatty liver and reduced activity. Increasing AS3MT in liver cells restores energy and protects against arsenic damage,
Patrice Delaney +10 more
wiley +1 more source
Embryonic globins of the marsupial the Tammar Wallaby (Macropus Eugenii): bird like and mammal like.
, 1998 Examines the characterization and sequencing of the embryonic globins of the Tammar Wallaby. Determination of the provisional phylogenetic tree of beta-like globins; Description of the Tammar Wallaby; Properties of the embryonic type blood of the Tammar ...
Holland, Robert A. +2 more
core
Transfusion, EarlyView.Abstract Background ABO‐incompatible (ABOi) hematopoietic stem cell transplantation (HSCT) is often associated with ABO discrepancies post‐HSCT. Re‐emergence of the patient's original type post‐HSCT may signal graft loss, disease relapse, recent transfusion, or soluble ABO antigen.
Sheri Hugan, Nada Naiyer, Laura Cooling
wiley +1 more source
, 2015 Globins identified in the latest annotation of the S. purpuratus genome sequence, Spur_v3.1 (2011/06/10).
Maurice R. Elphick (138400) +9 more
core +1 more source
Transfusion, EarlyView.Abstract Background Acute pain transfusion reaction (APTR) is a rare, under‐recognized condition of unknown etiology. It can cause significant distress in recipients, necessitating symptomatic management and, occasionally, hospitalization. Study Design and Methods Here, we present an APTR event in an adult subject with transfusion‐dependent thalassemia
Georgia Tzafa +20 more
wiley +1 more source