Results 121 to 130 of about 36,679 (341)

Matrix: a complex amalgam of structures and functions in tumor microenvironment

FEBS Open Bio, EarlyView.
The matrix is a dynamic, intricate three‐dimensional mesh of biomolecules with both structural and functional properties. This review deals with the complexity of this ‘molecular amalgam’ in the tumor microenvironment and highlights its importance in the maintenance and evolution of tumors by describing certain matrix biomolecules, such as ...
Spyros S. Skandalis, Evgenia Tsoukala, Theodora D. Sarantopoulou, Maria‐Elpida Christopoulou   +3 more
wiley   +1 more source

Another Faint UV Object Associated with a Globular Cluster X-Ray Source: The Case of M92

, 2000
The core of the metal poor Galactic Globular Cluster M92 (NGC 6341) has been observed with WFPC2 on the Hubble Space Telescope through visual, blue and mid-UV filters in a program devoted to study the evolved stellar population in a selected sample of ...
Barbara Paltrinieri, Buonanno R., Cool A. M., Ferraro F. R., Flavio Fusi Pecci, Fox D., Francesco R. Ferraro, Hakala P. J., Hasinger G., Johnston H. M., Naylor T., Oosterhoff P. T., Richer H. B., Robert T. Rood, Roberto Buonanno, Verbunt F., Verbunt F., Verbunt F., Warner B.   +18 more
core   +1 more source

NMR screening of low molecular weight inhibitors targeting the papain‐like protease (PLPro) of SARS‐CoV‐2

FEBS Open Bio, EarlyView.
Papain‐like protease from SARS‐CoV‐2 plays an important role in the cleavage of the viral polyproteins and in the suppression of the host's immune response. Here, we present the results of an NMR screening study. We identified 86 binding compounds, of which five candidates were chosen for in‐depth analysis.
Dennis J. Pyper, Sridhar Sreeramulu, Benjamin T. Lanham, Elizabeth M. Engle, David Fushman, Harald Schwalbe   +5 more
wiley   +1 more source

Stromagenesis and cancer‐associated fibroblast heterogeneity in primary tumors and metastasis: focus in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
Cancer‐associated fibroblasts (CAFs) play different roles in NSCLC progression and metastasis. Their heterogeneous origins and phenotypes shape the tumor microenvironment and influence metastatic spread. This review highlights NSCLC CAF subtypes, their potential cellular sources, and their differential distribution across primary tumors and distant ...
Alejandro Bernardo, Natalia Díaz‐Valdivia, Patricia Fernández‐Nogueira, Jordi Alcaraz   +3 more
wiley   +1 more source

Hot Stars in Globular Clusters: A Spectroscopist’s View [PDF]

Publications of the Astronomical Society of the Pacific, 2001
Globular clusters are ideal laboratories to study the evolution of low-mass stars. In this work we concentrate on three types of hot stars observed in globular clusters: horizontal branch stars, UV bright stars, and white dwarfs. After providing some historical background and information on gaps and blue tails we discuss extensively hot horizontal ...
openaire   +4 more sources

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

PHANGS Hubble Space Telescope Treasury Survey: Globular Cluster Systems in 17 Nearby Spiral Galaxies

The Astronomical Journal
We present new catalogs of likely globular clusters (GCs) in 17 nearby spiral galaxies studied as part of the PHANGS Hubble Space Telescope (HST) Treasury Survey.
Matthew Floyd, Rupali Chandar, Bradley C. Whitmore, David A. Thilker, Janice C. Lee, Rachel E. Pauline, Zion L. Thomas, William J. Berschback, Kiana F. Henny, Daniel A. Dale, Ralf S. Klessen, Eva Schinnerer, Kathryn Grasha, Médéric Boquien, Kirsten L. Larson, Sinan Deger, Ashley T. Barnes, Adam K. Leroy, Erik Rosolowsky, Thomas G. Williams, Leonardo Úbeda   +20 more
doaj   +1 more source

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

FEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado, Leanne Jones, Sonika Divakar, Michael Naidoo, Karen Anthony   +4 more
wiley   +1 more source

JWST NIRCam Observations of the Globular Cluster Population of RXJ 2129.7+0005

The Astrophysical Journal
We present an analysis of the globular cluster (GC) population in the galaxy cluster RXJ 2129.7+0005 ( z = 0.234) based on JWST NIRCam imaging in three filters: F115W, F150W, and F200W.
Kaitlyn E. Keatley, William E. Harris
doaj   +1 more source

Globular Clusters and the Halos of Dwarf Galaxies

Galaxies, 2017
Many dwarf galaxies have disproportionately rich globular cluster (GC) systems for their luminosities. Moreover, the GCs tend to be preferentially associated with the most metal-poor stellar populations in their parent galaxies, making them attractive ...
Søren S. Larsen
doaj   +1 more source