Results 121 to 130 of about 87,149 (376)

A Population of Massive Globular Clusters in NGC 5128

open access: yes, 2004
We present velocity dispersion measurements of 14 globular clusters in NGC 5128 (Centarus A) obtained with the MIKE echelle spectrograph on the 6.5m Magellan Clay telescope.
Battistini P.   +8 more
core   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

First Starbursts at high redshift: Formation of globular clusters

open access: yes, 2003
Numerical simulations of a Milky Way-size galaxy demonstrate that globular clusters with the properties similar to observed can form naturally at z > 3 in the concordance Lambda-CDM cosmology.
A. V. Kravtsov   +4 more
core   +1 more source

Variable stars in the globular cluster M 92 [PDF]

open access: yesAstronomy & Astrophysics, 2001
AbstractResults of a search for variable stars in the central region of the Oosterhoff II type globular cluster M92 are presented.
openaire   +2 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Dark Matter Halos in Galaxies and Globular Cluster Populations

open access: yes, 2014
We combine a new, comprehensive database for globular cluster populations in all types of galaxies with a new calibration of galaxy halo masses based entirely on weak lensing.
Harris, Gretchen L.   +2 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

oMEGACat. IV. Constraining the Ages of Omega Centauri Subgiant Branch Stars with HST and MUSE

open access: yesThe Astrophysical Journal
We present age estimates for over 8100 subgiant branch (SGB) stars in Omega Centauri ( ω Cen) to study its star formation history. Our large data set, which combines multi-wavelength Hubble Space Telescope photometry with MUSE metallicities, provides an ...
C. Clontz   +15 more
doaj   +1 more source

Constraining globular cluster formation through studies of young massive clusters – IV. Testing the fast rotating massive star scenario [PDF]

open access: yes, 2014
One of the leading models for the formation of multiple stellar populations within globular clusters is the "Fast Rotating Massive Star" (FRMS) scenario, where the ejecta of rapidly rotating massive stars is mixed with primordial material left over from ...
N. Bastian   +2 more
semanticscholar   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

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