Results 51 to 60 of about 1,255,310 (311)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A JWST Project on 47 Tucanae: NIRSpec Spectroscopy of Multiple Populations among M Dwarfs

The Astrophysical Journal Letters
We present the first spectroscopic estimates of the chemical abundance of M dwarf stars in a globular cluster (GC), namely 47 Tucanae. By exploiting NIRSpec on board the James Webb Space Telescope, we gathered low-resolution spectra for 28 stars with ...
A. F. Marino, A. P. Milone, A. Renzini, E. Dondoglio, E. Bortolan, M. G. Carlos, G. Cordoni, A. Dotter, S. Jang, E. P. Lagioia, M. V. Legnardi, F. Muratore, A. Mohandasan, M. Tailo, T. Ziliotto   +14 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Star-crossed Clusters: Asteroseismic Ages for Individual Stars Are in Tension with the Ages of Their Host Clusters

The Astrophysical Journal Letters
A meta-analysis of seismic ages determined for individual stars in the well-studied open and globular clusters NGC 6819, NGC 6791, M67, M4, M19, M80, and M9 reveals both high variance across measurements and a possible discrepancy with independent ...
Jamie Tayar, Meridith Joyce
doaj   +1 more source

r-process Abundance Patterns in the Globular Cluster M92

The Astrophysical Journal, 2023
Whereas light-element abundance variations are a hallmark of globular clusters, there is little evidence for variations in neutron-capture elements. A significant exception is M15, which shows a star-to-star dispersion in neutron-capture abundances of at
Evan N. Kirby, Alexander P. Ji, Mikhail Kovalev   +2 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Modeling Formation of Globular Clusters: Beacons of Galactic Star Formation

, 2010
Modern hydrodynamic simulations of galaxy formation are able to predict accurately the rates and locations of the assembly of giant molecular clouds in early galaxies.
Oleg Y. Gnedin
core   +1 more source

A Massive Neutron Star in the Globular Cluster M5 [PDF]

The Astrophysical Journal, 2008
10 pages in ApJ emulate format, 2 tables, 6 figures. Added February 2008 data, slightly revised mass limits.
Freire, P.C.C., Wolszczan, A., van den Berg, M., Hessels, J.W.T.   +3 more
openaire   +3 more sources

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source