Results 61 to 70 of about 2,490 (267)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Variable stars in the VVV globular clusters

Astronomy & Astrophysics
Context. High reddening near the Galactic plane hampers observations and proper characterization of the globular clusters (GCs) located toward the inner regions of the Milky Way. Aims. The VISTA Variables in the Vía Láctea (VVV) survey observed the Galactic bulge and adjacent disk for several years, providing multi-epoch, near-infrared images for 41 ...
Javier Alonso-García, Leigh C. Smith, Jason L. Sanders, Dante Minniti, Márcio Catelan, Gonzalo Aravena Rojas, Julio A. Carballo-Bello, José G. Fernández-Trincado, Carlos E. Ferreira Lopes, Elisa R. Garro, Zhen Guo, Maren Hempel, Philip W. Lucas, Daniel Majaess, Roberto K. Saito, A. Katherina Vivas   +15 more
openaire   +2 more sources

Spectroscopy of Main-Sequence and Subgiant Stars in Globular Star Clusters [PDF]

Symposium - International Astronomical Union, 1984
Since the mid-1970's it has been apparent that giant stars of similar V and B-V within a “normal” globular cluster [i.e., one with a narrow giant branch in its color-magnitude diagram (CMD)] exhibit a perplexing range of strengths for such spectral features as CH, CN and NH.
James E. Hesser, Gretchen L.H. Harris, R.A. Bell, R.D. Cannon   +3 more
openaire   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

The ESO-VLT MIKiS Survey Reloaded: Exploring the Internal Kinematics of NGC 6440

The Astrophysical Journal, 2023
In the context of the ESO-VLT Multi-Instrument Kinematic Survey of Galactic globular clusters, here we present the line-of-sight velocity dispersion profile of NGC 6440, a massive globular cluster located in the Galactic bulge.
Silvia Leanza, Cristina Pallanca, Francesco R. Ferraro, Barbara Lanzoni, Emanuele Dalessandro, Mario Cadelano, Enrico Vesperini, Livia Origlia, Alessio Mucciarelli, Elena Valenti   +9 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Utilizing Voronoi Tessellations to Determine Radial Density Profiles

The Astronomical Journal
We have developed a novel method of determining 2D radial density profiles for astronomical systems of discrete objects using Voronoi tessellations. This Voronoi-based method was tested against the standard annulus-based method on five simulated systems ...
Veronika Dornan, William E. Harris
doaj   +1 more source

Retention fractions for globular cluster neutron stars [PDF]

Monthly Notices of the Royal Astronomical Society, 1996
To appear in MNRAS, 15 pages, LaTeX, requires MN and epsf styles, includes 3 PS Figures, compressed, uuencoded ...
openaire   +2 more sources