Results 21 to 30 of about 66,871 (257)

Globular cluster ages [PDF]

open access: yesProceedings of the National Academy of Sciences, 1998
We review two new methods to determine the age of globular clusters (GCs). These two methods are more accurate than the classical isochrone fitting technique. The first method is based on the morphology of the horizontal branch and is independent of the distance modulus of the globular cluster.
openaire   +2 more sources

Secondary Globular Cluster populations [PDF]

open access: yesAstronomy & Astrophysics, 2004
18 pages, 7 figures, accepted for A& ...
openaire   +3 more sources

Developmental and Genetic Constraints on Neurocranial Globularity: Insights from Analyses of Deformed Skulls and Quantitative Genetics

open access: yesEvolutionary biology, 2009
Neurocranial globularity is one of the few derived traits defining anatomically modern humans. Variations in this trait derive from multiple and complex interactions between portions of the brain and the size and shape of the cranial base, among other ...
Neus Martínez‐Abadías   +4 more
semanticscholar   +1 more source

Evaluation of the structural quality of modeled proteins by using globularity criteria

open access: yesBMC Structural Biology, 2007
BackgroundThe knowledge of the three-dimensional structure of globular proteins is fundamental for a detailed investigation of their functional properties.
Susan Costantini   +2 more
semanticscholar   +1 more source

The evolution of modern human brain shape

open access: yesScience Advances, 2018
The evolutionary process leading to human brain globularity was gradual and paralleled the emergence of behavioral modernity. Modern humans have large and globular brains that distinguish them from their extinct Homo relatives.
Simon Neubauer, J. Hublin, P. Gunz
semanticscholar   +1 more source

QSAR-based molecular signatures of prenylated (iso)flavonoids underlying antimicrobial potency against and membrane-disruption in Gram positive and Gram negative bacteria

open access: yesScientific Reports, 2018
Prenylated flavonoids and isoflavonoids are phytochemicals with remarkable antibacterial activity. In this study, 30 prenylated (iso)flavonoids were tested against Listeria monocytogenes and Escherichia coli (the latter in combination with an efflux pump
Carla Araya-Cloutier   +6 more
semanticscholar   +1 more source

Like father, like son: assessment of the morphological affinities of A.L. 288-1 (A. afarensis), Sts 7 (A. africanus) and Omo 119-73-2718 (Australopithecus sp.) through a three-dimensional shape analysis of the shoulder joint.

open access: yesPLoS ONE, 2015
The postcranial evidence for the Australopithecus genus indicates that australopiths were able bipeds; however, the morphology of the forelimbs and particularly that of the shoulder girdle suggests that they were partially adapted to an arboreal ...
Julia Arias-Martorell   +3 more
doaj   +1 more source

Mucoadhesive Polymer Hyaluronan as Biodegradable Cationic/Zwitterionic-Drug Delivery Vehicle

open access: yesADMET and DMPK, 2015
Mucoadhesive polymers in pharmaceutical formulations release drugs in mucosal areas. They interact and fix to mucus via molecular interpenetration, etc., which increase drug bioavailability.
Francisco Torrens, Gloria Castellano
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

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