Unleashing the power of complement activation: unraveling renal damage in human anti-glomerular basement membrane disease [PDF]
Anqi Tang +6 more
openalex +1 more source
L‐theanine alleviates alcohol exposure‐induced kidney injury through a multiple mechanisms. ABSTRACT Alcohol exposure induces kidney oxidative stress and inflammatory responses. L‐theanine (LTA) can protect the kidneys through its antioxidant and immunomodulatory effects; however, its role and underlying mechanisms in alleviating alcoholic kidney ...
Xuhui Dang +6 more
wiley +1 more source
IgG4-Restricted Anti–Glomerular Basement Membrane Autoantibodies Targeting Quaternary Epitopes of Native α345(IV) Collagen [PDF]
Dorin‐Bogdan Borza
openalex +1 more source
Abstract Preservation of the insulin‐sensitive glomerular podocyte is imperative for normal kidney function. The protein tyrosine phosphatases (PTPs), protein tyrosine phosphatase 1B (PTP1B), T‐cell protein tyrosine phosphatase (TCPTP), and Src homology phosphatase 2 (SHP2) are established regulators of insulin signaling in vivo and implicated in renal
Grace LeBleu +6 more
wiley +1 more source
Mastering Organoid Growth: A Complete Guide to Overcoming Methodological Challenges
Organoids offer transformative 3D models that precisely mimic human organ architecture and function. This review details the latest methodology, emphasizing the cultivation of liver and other abdominal organoids. We analyze technological challenges (e.g., nutrient delivery, scalability, diversity) and provide practical insights for new researchers ...
Chunbao Jiao +12 more
wiley +1 more source
Inhibition of CXCL16 Attenuates Inflammatory and Progressive Phases of Anti-Glomerular Basement Membrane Antibody-Associated Glomerulonephritis [PDF]
Gabriela E. Garcia +6 more
openalex +1 more source
The management of cancer and tissue regeneration remains a substantial challenge to global health. Organoids, which are stem cell‐derived three‐dimensional multicellular structures, are revolutionizing biomedical research. Therefore, this review highlights their applications in cancer research and regenerative medicine, while discussing current ...
Ruiyang Li +5 more
wiley +1 more source
Sequential occurrence of anti-glomerular basement membrane disease 9 years after anti-neutrophil cytoplasmic antibody-associated vasculitis [PDF]
Pui Shan Julia Chan, Moon Ho Leung
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LPS‐stimulated DC activation upregulated DBC1. DBC1‐deficient DC ameliorated murine SLE symptoms. DBC1 deficiency suppressed immune responses in DC. DBC1 deficiency lowered STAT5 expression and subsequent phosphorylation. STAT5 overexpression abolished murine SLE remission primed by DBC1 deficiency.
Ze Xiu Xiao +9 more
wiley +1 more source
Rapidly Progressive Glomerulonephritis with Delayed Appearance of Anti-Glomerular Basement Membrane Antibody Successfully Treated with Multiple Courses of Steroid Pulse Therapy [PDF]
Satoshi Toyota +10 more
openalex +1 more source

