Results 91 to 100 of about 36,211 (244)

Proteolytic remodelling of the extracellular matrix by pericytes

The FEBS Journal, EarlyView.
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard, Ella Milne, Kate Qian, Paola Campagnolo, Salvatore Santamaria   +4 more
wiley   +1 more source

Glomerular plasmalemma vesicle‐associated protein‐1 as an endothelial remodelling marker complementing C4d in chronic active antibody‐mediated rejection

Histopathology, EarlyView.
Glomerular plasmalemma vesicle‐associated protein‐1 (PV‐1/PLVAP) identifies dynamic endothelial remodelling in chronic active antibody‐mediated rejection (caABMR), complementing glomerular C4d, which reflects a static footprint of complement activation. Combined assessment of PV‐1 and C4d captures complementary dimensions of microvascular pathology and
Yuto Igarashi, Mayu Shimokawa, Kunio Kawanishi, Toshihito Hirai, Hiroshi Seino, Tomokazu Shimizu, Hideki Ishida, Toshio Takagi   +7 more
wiley   +1 more source

Recurrent anti-GBM disease with pulmonary artery aneurysms

JRSM Open, 2016
We present the first known case of pulmonary artery aneurysms as a feature of Recurrent Anti-Glomerular Basement Membrane disease.
John Dixon, Hannah Wilkinson, Kamran Iqbal, Virginia Quan   +3 more
doaj   +1 more source

Laminin distribution in developing glomerular basement membranes

, 1993
Laminin distribution in developing glomerular basement membranes. The renal glomerular basement membrane (GBM) separates two distinctly different cell layers: the vascular endothelium, and visceral epithelial podocytes.
St John, Patricia L., Abrahamson, Dale R.   +1 more
core   +1 more source

Maladie des anticorps anti-membrane basale glomérulaire [Anti-glomerular basement membrane disease]

, 2023
Anti-glomerular basement membrane disease is a rare disease. In its classical presentation it associates rapidly progressive glomerulonephritis and diffuse alveolar hemorrhage, linked to the presence of antibodies targeting type IV collagen in the ...
Daccord, C., Stevanin, M., Kissling, S., Rotman, S., Comte, D., Ribi, C.   +5 more
core   +1 more source

Clinical implications of imlifidase interference in antibody screening and transfusion management

Transfusion, EarlyView.
Abstract Background Imlifidase has received conditional approval from the EMA for desensitizing deceased donor kidney transplant recipients. It works by cleaving IgG into F(ab′)2 and Fc fragments, thereby reducing the risk of antibody‐mediated rejection. However, its impact on diagnostic assays remains understudied. Case Report We present the case of a
Zgjim Osmani, Aiko P. J. de Vries, Arjan Albersen   +2 more
wiley   +1 more source

Electron Microscopic and Immunohistochemical Findings of the Epidermal Basement Membrane in Two Families with Nail-patella Syndrome

Acta Dermato-Venereologica, 2019
Nail-patella syndrome is an autosomal dominant disorder characterized by nail dysplasia and skeletal anomaly. Some patients have been shown to have ultrastructural abnormalities of the glomerular basement membrane that result in nephrosis.
Satoru Shinkuma, Hideki Nakamura, Manami Maehara, Shota Takashima, Toshifumi Nomura, Yasuyuki Fujita, Satoshi Hasegawa, Kazuko C. Sato-Matsumura, Riichiro Abe, Hiroshi Shimizu   +9 more
doaj   +1 more source

CHARACTERIZATION OF CANINE GLOMERULAR BASEMENT MEMBRANE.

, 1965
CHARACTERIZATION OF CANINE GLOMERULAR BASEMENT ...
NICHOLAS ALEXANDER. KEFALIDES (7974611)
core  

Reduction of anionic sites in the glomerular basement membrane by heparanase does not lead to proteinuria. [PDF]

, 2008
Contains fulltext : 71200.pdf (Publisher’s version ) (Open Access)Heparan sulfate in the glomerular basement membrane has been considered crucial for charge-selective filtration.
Heuvel, L.P.W.J. van den, Lensen, J.F., van der Vlag, J, van den Heuvel, L P, Wijnhoven, T.J.M., Wijnhoven, T J, Zcharia, E., Wismans, R.G., Dijkman, H B, van Kuppevelt, T H, Li, J.P., Dijkman, H.B., Kuppevelt, A.H.M.S.M. van, van den Hoven, M.J., Dijkman, H.B.P.M., van Kuppevelt, T.H., Wijnhoven, T.J., Rops, A L, Rops, A.L., van der Vlag, J., Berden, J H M, Berden, J.H.M., van den Hoven, M J, van den Heuvel, L.P., Lensen, J F, Vlag, J. van der, Wismans, R G, Lensen, J.F.M., Vlodavsky, I, Vlodavsky, I., Li, J.-P., Wismans, P.G.P., Zcharia, E, Li, Jin-Ping,, Hoven, M.J.W. van den, Rops, L.W.M.M.   +35 more
core   +1 more source

Role of RIPK1/RIPK3/MLKL signalling pathway in sepsis‐associated acute kidney injury

Experimental Physiology, EarlyView.
Abstract Sepsis‐associated acute kidney injury (SA‐AKI) is a common clinical syndrome in critically ill patients, and its high mortality rate is closely related to complex pathological mechanisms. Existing studies have shown that the pathophysiological process of SA‐AKI involves complex multi‐mechanism interactions, including an uncontrolled systemic ...
Huijun Yin, Jingyi Wang, Huirong Han
wiley   +1 more source