Results 81 to 90 of about 32,626 (197)
Splitting of the Glomerular Basement Membrane [PDF]
Postgraduate Medical Journal, 1962 A, Fabbrini, G A, Cinotti, F, Giacomelli
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Applications of Bioinorganic Nano‐Based Delivery Systems—Diagnostics and Therapeutics
Drug Development Research, Volume 87, Issue 5, August 2026.ABSTRACT Nanotechnology has emerged as a promising avenue for producing nanomedicines as alternatives to conventional drugs. Many organic nanoparticles, such as liposomes used in formulations like Doxil, Onivyde, and Marqibo, are approved by the Food and Drug Administration (FDA) and instrumental in treating various types of cancers.
Frank Ssengooba +2 more
wiley +1 more source
Temporal Clustering of Antiglomerular Basement Membrane Disease in COVID-19 Pandemic: A Case Series
International Journal of Nephrology and Renovascular Disease, 2021 Rakesh Sebastian, Jegan Arunachalam, Manorajan Rajendran Department of Nephrology, Government Rajaji Hospital, Madurai Medical College, Madurai, Tamil Nadu, IndiaCorrespondence: Jegan ArunachalamDepartment of Nephrology, Government Rajaji Hospital ...
Sebastian R, Arunachalam J, Rajendran M
doaj
Health Science Reports, Volume 9, Issue 8, August 2026.ABSTRACT Background and Aims Hypertension (HTN) is a long‐term condition marked by consistently high arterial blood pressure. It is a leading contributor to cardiovascular diseases and early mortality around the globe. It increases the risk of ischemic heart disease, stroke, chronic kidney disease (CKD), and dementia.
Amanuel Hika +5 more
wiley +1 more source
Journal of Diabetes, Volume 18, Issue 8, August 2026.This study identifies a novel pathogenic pathway in DN wherein hyperglycemia‐induced ELAVL1 upregulates PLAUR expression and promotes suPAR release from podocytes, leading to renal inflammation and injury. ABSTRACT Background Diabetic nephropathy (DN) is a leading cause of end‐stage renal disease.
DanDan Xu, Liang Xu, LinLin Li
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Aging Cell, Volume 25, Issue 8, August 2026.Aging is associated with impaired TFEB‐dependent autophagy in renal proximal tubular epithelial cells, leading to increased susceptibility to LPS‐induced injury and inflammation. Restoration of autophagy through TFEB activation or Tat–Beclin 1 treatment partially rescues autophagic function and confers protection against elderly sepsis‐associated acute
Yu Xiang +7 more
wiley +1 more source
Nephropathies with pattern of structural alterations of the glomerular basement membrane: Case study
Revista Médica del Hospital General de México, 2018 Background: The pattern of structural alterations of the glomerular basement membrane comprises two hereditary glomerular diseases: Alport syndrome (AS) and thin basement membrane nephropathy (TBMN); both are rare entities.
L.A. Pedroza, M.V. Soto-Abraham
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Glomerular Basement Membrane [PDF]
Journal of Biological Chemistry, 1998 Sripad Gunwar +5 more
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Identification of drug repurposing candidates for the treatment of polycystic kidney disease
British Journal of Pharmacology, Volume 183, Issue 16, Page 5082-5101, August 2026.Background and Purpose Autosomal dominant polycystic kidney disease (ADPKD) is a leading cause of end‐stage renal disease with limited treatment options. Drug repurposing offers a promising strategy to find effective treatments. Experimental Approach We identified birinapant, bardoxolone methyl and salicylic acid as repurposing candidates for ADPKD and
Alina Meyer +9 more
wiley +1 more source
Fn14 signalling participates in pristane‐induced murine lupus through exacerbating oxidative stress
British Journal of Pharmacology, Volume 183, Issue 16, Page 5102-5119, August 2026.Background and Purpose Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by oxidative stress and immune dysregulation. Fibroblast growth factor‐inducible 14 (Fn14) has been implicated in tissue injury, but its specific role in SLE pathogenesis remains unclear.
Zhu Yan +8 more
wiley +1 more source