Results 131 to 140 of about 108,933 (325)

Counting glomeruli in human kidney specimens using ex vivo MRI without contrast agents

open access: yesMagnetic Resonance in Medicine, Volume 94, Issue 6, Page 2519-2528, December 2025.
Abstract Purpose The total number of glomeruli is an important indicator of kidney function and susceptibility to disease. Glomeruli, however, are difficult to image using MRI without contrast enhancement. For this reason, previous studies have used cationic ferritin as a contrast agent to detect glomeruli in ex vivo and in vivo perfused kidneys.
Nyoman D. Kurniawan   +11 more
wiley   +1 more source

The Heparanase Inhibitor (Sulodexide) Decreases Urine Glycosaminoglycan Excretion and Mitigates Functional and Histological Renal Damages in Diabetic Rats

open access: yesActa Medica Bulgarica, 2019
Background/objectives: Recent data suggest a role for heparanase in several proteinuric conditions. An increased glomerular heparanase expression is associated with loss of heparan sulfate in the glomerular basement membrane (GBM). The aim of the present
Roshan-Milani S.   +2 more
doaj   +1 more source

Molecular and Cellular Events Mediating Glomerular Podocyte Dysfunction and Depletion in Diabetes Mellitus

open access: yesFrontiers in Endocrinology, 2014
The essential function of the kidney is to ensure formation of relatively protein-free ultra-filtrate, urine. The rate of filtration and composition of the primary renal filtrate is determined by the transport of fluid and solutes across the glomerular ...
Ram K Menon   +3 more
doaj   +1 more source

Characterization of novel glomerular proteins : role in physiology and disease [PDF]

open access: yes, 2014
Glomerular damage accounts for the majority of chronic kidney disease cases, the prevalence of which is dramatically escalating worldwide, mainly due to increase in diabetes and associated nephropathy.
Andersson, Ann-Charlotte
core   +1 more source

A Case of Myeloproliferative Neoplasm‐Associated Glomerulopathy in a Patient With Myelofibrosis

open access: yesClinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT Myeloproliferative neoplasm (MPN)‐related glomerulopathy is a rare, late complication of MPN. Mesangial matrix expansion seems to be the histopathological hallmark. Proteinuria may not always be present. Further exploration is warranted to determine whether risk factors—including disease entity, mutation status and treatment regimens ...
Saskia Leibowitz   +4 more
wiley   +1 more source

A glomerulus-on-a-chip to recapitulate the human glomerular filtration barrier

open access: yesNature Communications, 2019
The glomerular filtration barrier is a complex structure in charge of renal ultrafiltration. Here the authors present a glomerulus-on-a-chip for disease modelling and high-throughput drug screening where human podocytes and human glomerular endothelial ...
Astgik Petrosyan   +8 more
doaj   +1 more source

Glomerular basement membrane necrosis and crescent organization

open access: yesKidney International, 1988
In order to reveal structural damage to the glomerular basement membranes occurring in crescentic glomerulonephritis and the subsequent connective tissue organization of the crescent, 14 kidney biopsies were treated with detergents to remove cellular components and the tissue remaining examined by transmission (TEM) and scanning (SEM) electron ...
Stephen M. Bonsib, Stephen M. Bonsib
openaire   +3 more sources

Goodpasture's Syndrome: Treatment With Nephrectomy and Renal Transplantation [PDF]

open access: yes, 1971
Three young male patients developed acute glomerulonephritis and serious hemoptysis. All three had evidence of antiglomerular basement membrane (anti-GBM) antibodies in their serum and native kidneys.
Anderson, JT   +6 more
core   +1 more source

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