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Glomerular Basement Membrane Autoantibodies
2014Partie 10, Chapitre 65 ; International ...
Luque-Paz, Damien +2 more
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Anti-glomerular basement membrane vasculitis
Autoimmunity Reviews, 2023Antiglomerular basement membrane disease (anti-GBM) is a rare life-threatening autoimmune vasculitis that involves small vessels and it is characterized by circulating autoantibodies directed against type IV collagen antigens expressed in glomerular and alveolar basement membrane.
Claudio, Ponticelli +2 more
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Dual origin of glomerular basement membrane
Developmental Biology, 1984The histogenesis of renal basement membranes was studied in grafts of avascular, 11-day-old mouse embryonic kidney rudiments grown on chick chorioallantoic membrane (CAM). Vessels of the chick CAM invade the mouse tissue during an incubation period of 7-10 days and eventually hybrid glomeruli composed of mouse epithelium and chick endothelium form ...
Sariola, H +6 more
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Pathology of glomerular basement membrane nephropathy
Current Opinion in Nephrology and Hypertension, 1994Studies of the molecular pathology of glomerular basement membrane have led to the discovery of four novel chains of type IV collagen, the latest of which is the alpha 6(IV) chain. Three chains have been shown to be directly involved in the pathogenesis of Goodpasture syndrome, Alport syndrome, and Alport posttransplantation antiglomerular basement ...
B G, Hudson, R, Kalluri, K, Tryggvason
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2010
The glomerular basement membrane shown in panel A differs from basement membranes in other locations in that it is faced by a cell layer on either side, namely the endothelia and the podocytes and that it is thicker, because it is the product of fusion of the basement membrane of endothelial cells and podocytes.
Margit Pavelka, Jürgen Roth
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The glomerular basement membrane shown in panel A differs from basement membranes in other locations in that it is faced by a cell layer on either side, namely the endothelia and the podocytes and that it is thicker, because it is the product of fusion of the basement membrane of endothelial cells and podocytes.
Margit Pavelka, Jürgen Roth
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Molecular Sieving by Glomerular Basement Membrane
Nature, 1967OF the three layers of the glomerular capillary wall—endothelial cells, basement membrane and epithelial cells—the basement membrane appears to be the only complete barrier between the plasma and the glomerular filtrate1,2. Support for the view that the basement membrane is the most important filtering mechanism was provided by the studies on ferritin ...
F, Huang, L, Hutton, N, Kalant
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Antigens of the human glomerular basement membrane
Springer Seminars in Immunopathology, 1987The intent of the previous discussion has been to acquaint the reader with the recent expanding knowledge in matrix biochemistry and immunopathology as it pertains to the human GBM. However, it must be emphasized that the GBM antigens, which have yet to be characterized, may outnumber those that are currently defined.
L S, Fouser, A F, Michael
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Glomerular basement membrane as a compressible ultrafilter
Microvascular Research, 1989The ultrafiltration properties of isolated glomerular basement membrane were studied in vitro by forming membrane fragments into thin films for use as ultrafiltration membranes. The filtration properties of the films were examined using cytochrome c, myoglobin, lysozyme, ovalbumin, lactoglobulin, and serum albumin.
Robinson, G B, Walton, H A
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Inherited Diseases of the Glomerular Basement Membrane
American Journal of Kidney Diseases, 1994The inherited diseases of the glomerular basement membrane include Alport's syndrome (AS), nail-patella syndrome, and thin basement membrane nephropathy. Classical AS is inherited in an X-linked manner and accounts for approximately 85% of the cases. Its manifestations include hematuria, sensorineural hearing loss, ocular defects, and a progression to ...
K A, Bodziak +2 more
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Inherited diseases of the glomerular basement membrane
Nature Clinical Practice Nephrology, 2008The glomerular basement membrane (GBM) is a specialized form of basement membrane that has a major role in the maintenance of the glomerular filtration barrier. Like all basement membranes, it contains four main components: type IV collagen, laminin, nidogen, and heparan sulfate proteoglycans.
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