Results 141 to 150 of about 36,211 (244)

A Case Report of a Special Type of Multiple Myeloma: Kappa Light Chain‐Only

Organ Medicine, Volume 3, Issue 2, Page 119-124, June 2026.
This case illustrates the clinical course of a patient diagnosed with kappa light chain‐only multiple myeloma, a rare subtype of multiple myeloma. Of note, light chain multiple myeloma is characterized by rapid disease progression and severe target organ damage.
Yanhua Dai, Yuanyue Guan, Shiwei Cui, Yuan Gao, Zhipeng Zhao, Rui Li, Li Song, Xiuying Zhao, Runqing Li   +8 more
wiley   +1 more source

Molecular sieve of the rat glomerular basement membrane: a transmission electron microscopic study of enzyme-treated specimens.

, 1988
Isolated rat glomerular basement membrane was treated with elastase and observed by transmission electron microscopy. The treatment with elastase revealed the fundamental structure of the glomerular basement membrane quite clearly, and enabled the ...
Ichiyasu, Akira, Makino, Hirofumi
core   +1 more source

Morphological and Biochemical Insights Into the Renoprotective Effects of Combined N‐Acetylcysteine and Glycine Treatment in Experimental Diabetic Nephropathy

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Diabetic nephropathy (DN) is a major microvascular complication of diabetes mellitus and the leading cause of end‐stage renal disease. Oxidative stress and inflammation are central drivers of DN progression, yet no effective therapies exist to prevent or delay renal injury. This study investigated the renoprotective effects of glycine (GLY), N‐
Malik Ejubović, Andrej Belančić, Yun Wah Lam, Farideh Javid, Dina Kapić, Esad Ćosović, Rijad Jahić, Orhan Lepara, Amira Jagodić Ejubović, Lejla Alić, Amil Topuz, Zurifa Ajanović, Almir Fajkić   +12 more
wiley   +1 more source

Basement membrane proteoglycans in glomerular morphogenesis: chondroitin sulfate proteoglycan is temporally and spatially restricted during development.

, 1993
Udgivelsesdato: 1993-MarWe previously reported the presence of a basement membrane-specific chondroitin sulfate proteoglycan (BM-CSPG) in basement membranes of almost all adult tissues.
McCarthy, K J, Abrahamson, D R, Couchman, J R, St John, P L, Bynum, K   +4 more
core   +2 more sources

Glomerular basement membrane thickness in minimal change disease

, 2000
의학과/석사[한글] 사구체의 기저막은 전자 현미경 검색상 3층으로 구성되어 있으며 중심부에 전자 고밀도층인 lamina dense와 양측의 전자 밀도가 낮은 lamina rara interna와 lamina rara externa로 구성되어 있다. 사구체 기저막의 두께는 연령 및 성별에 따라 차이가 있으며 질병에 따라 비후 또는 얇아지기도 한다. 그러나 한국인의 정상 사구체 기저막 두께에 대한 자료는 증례 보고의 대조군 정도만 있을 뿐 연령별, 성별
김윤미
core  

Glomerular basement membrane necrosis and crescent organization

, 1988
Glomerular basement membrane necrosis and crescent organization. In order to reveal structural damage to the glomerular basement membranes occurring in crescentic glomerulonephritis and the subsequent connective tissue organization of the crescent, 14 ...
Bonsib, Stephen M.
core   +1 more source

Heparanase inhibition prevents glycocalyx damage and albuminuria in experimental minimal change disease

Clinical and Translational Medicine, Volume 16, Issue 6, June 2026.
Michael Crompton, Raina D. Ramnath, Kai Betteridge, Sara Desideri, Aldara Martin Alonso, Lulu Jiang, Monica Gamez, Holly Stowell‐Connolly, Viktoriia Vasylchenko, Karen L. Onions, Matthew J. Butler, Chris R. Neal, Andrew H. J. Salmon, Jeremy E. Turnbull, Hiroshi Kawachi, Olga V. Zubkova, Gavin I. Welsh, Simon C. Satchell, Rebecca R. Foster   +18 more
wiley   +1 more source

Multimodal Assessment of Kidney Quality During 24‐h of Normothermic Machine Perfusion

Artificial Organs, Volume 50, Issue 6, Page 851-865, June 2026.
Normothermic machine perfusion (NMP) has emerged as a promising tool for assessing kidney quality prior to transplantation; however, reliable biomarkers remain to be established. In this study, thirteen porcine kidneys were perfused for 24 h using an autologous leukocyte‐filtered whole blood‐based perfusate applying urine recirculation.
Marlene Pühringer, Magdalena Kött, Andras T. Meszaros, Michael J. Blumer, Bettina Zelger, Stefan Redl, Martin Hermann, Thomas Resch, Simon Mathis, Gabriel Putzer, Judith Martini, Christina Bogensperger, Franka Messner, Julia Hofmann, Margot Fodor, Andrea Griesmacher, Annemarie Weissenbacher, Theresa Hautz, Gert Mayer, Hannes Neuwirt, Gerald Brandacher, Silvia Oberparleiter, Stefan Schneeberger   +22 more
wiley   +1 more source

Mechanism of Fluid Reabsorption in Kidney Proximal Tubule: Interplay Between Lateral Na+/K+‐ATPase and AQP1 and SGLT1 Mediated Water Fluxes

Acta Physiologica, Volume 242, Issue 6, June 2026.
ABSTRACT Aims The mechanism of isosmotic water reabsorption in the kidney proximal tubule, with a focus on the interaction between the lateral Na+/K+‐ATPase, apical water pathways mediated by AQP1 and SGLT1, and paracellular water flow through Claudin‐2. Methods A mathematical model of proximal tubular transport was used to compute coupled ion, solute,
Erik Hviid Larsen, Jens Nørkær Sørensen   +1 more
wiley   +1 more source

Histopathological Assessment of Precision‐Cut Kidney Slices: A Live Human Tissue‐Based Model of Renal Fibrosis

APMIS, Volume 134, Issue 6, June 2026.
ABSTRACT Chronic kidney disease (CKD) is characterized by a progressive decline of renal function. A major challenge in CKD drug development is the low success rate of drug candidates, with fewer than 10% of drugs entering Phase I clinical trials demonstrating clinical benefit.
Andreas Riishede, Camilla Merrild, Seulgi Hyun, Mia G. Madsen, Anna K. Keller, Henricus A. M. Mutsaers, Rikke Nørregaard, Lene N. Nejsum   +7 more
wiley   +1 more source