A glomerulus-on-a-chip to recapitulate the human glomerular filtration barrier
The glomerular filtration barrier is a complex structure in charge of renal ultrafiltration. Here the authors present a glomerulus-on-a-chip for disease modelling and high-throughput drug screening where human podocytes and human glomerular endothelial ...
Astgik Petrosyan +8 more
doaj +1 more source
DEMONSTRATION OF CIRCULATING ANTIBODIES TO THE GLOMERULAR BASEMENT MEMBRANE [PDF]
David J. Evans, G. Manganella
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ABSTRACT Polymer scaffolds are a promising platform for the transplantation of insulin‐producing cells in Type 1 Diabetes. While vascularization has been a primary focus due to its role in oxygen and nutrient delivery, the interplay between blood vessels and the extracellular matrix (ECM) is increasingly recognized as critical for establishing a stable
Erika Pinheiro‐Machado +5 more
wiley +1 more source
Segmentation and Analysis of the Glomerular Basement Membrane in Renal Biopsy Samples Using Active Contours: A Pilot Study [PDF]
Rangaraj M. Rangayyan +2 more
openalex +1 more source
We report two cases of diffuse alveolar haemorrhage attributable to human metapneumovirus (hMPV), confirmed by PCR analysis of bronchoalveolar lavage fluid. Although the precise efficacy remains uncertain, both cases showed clinical improvement following short‐term corticosteroid therapy.
Masamichi Lee +5 more
wiley +1 more source
Pauci Immune crescentic glomerulonephritis in a patient with T-cell lymphoma and argyria [PDF]
Background Silver is a transition metal, toxic when ingested in significant amounts, causing argyria (skin deposition) and argyrosis (eye deposition).
Cunningham, J +6 more
core
This study identifies ferroptosis as a key driver of diabetes and its complications via iron metabolism and lipid peroxidation, elucidates organelle interactions underlying cell vulnerability, and provides insights for targeted therapies against metabolic disorders.
Zheng Wang +10 more
wiley +1 more source
Use of Plasmapheresis and Immunosuppressants to Treat Diffuse Alveolar Hemorrhage in a Patient with Granulomatosis with Polyangiitis. [PDF]
Granulomatosis with polyangiitis (GPA) is a systemic granulomatous inflammatory disease characterized by small-to-medium vessel vasculitis due to Central Anti-Neutrophil Cytoplasmic Antibody (C-ANCA).
Sattar, Yasar +4 more
core +1 more source
ANTI-GLOMERULAR BASEMENT MEMBRANE ANTIBODY-NEGATIVE, GOODPASTURE-LIKE ALVEOLAR HEMORRHAGE SYNDROME IN YOUNG WOMEN WITH METHAMPHETAMINE USE AND MANUFACTURE [PDF]
Carl A Kaplan +2 more
openalex +1 more source
On the measurement of glomerular filtration rate: An odyssey into the milieu intérieur
Experimental Physiology, EarlyView.
Anders Møller Greve +4 more
wiley +1 more source

