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Genetic Disorders of Glomerular Basement Membranes
Nephron Clinical Practice, 2010This review provides current information about glomerular disorders that arise directly from inherited abnormalities in extracellular matrix proteins intrinsic to the glomerular basement membrane (Alport syndrome, thin basement membrane nephropathy, HANAC syndrome and Pierson syndrome).
Clifford E, Kashtan, Yoav, Segal
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The deposition of silver in glomerular basement membrane
Virchows Archiv B Cell Pathology, 1972The sequential deposition of silver in glomerular basement membrane was studied electron microscopically in a series of rats which had ingested 12 mM AgNO3 drinking fluid continually for periods of up to 81 weeks.
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Glomerular Podocytes and Adhesive Interaction with Glomerular Basement Membrane
Nephron Experimental Nephrology, 1999Normal podocyte function requires attachment to the underlying glomerular basement membrane. Alteration or disruption of podocyte attachment occurs in many forms of glomerular injury, leading to the development of proteinuria and eventually progressive glomerulosclerosis.
P, Mundel, S J, Shankland
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VACUOLIZATION OF THE GLOMERULAR BASEMENT MEMBRANE
Acta Pathologica Microbiologica Scandinavica Section A Pathology, 1979Immunofluorescence and clinical data were collected retrospectively and renal tissue was examined by electron microscopy 1) for 20 consecutive patients whose glomeruli were normal in light microscopy except for vacuolization of obliquely‐cut portions of the glomerular basement membrane (GBM) after periodic acid‐silver‐methenamine staining, and 2) for ...
GUSTAV TALLQVIST +3 more
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The glomerular basement membrane in lupus nephritis
Microscopy Research and Technique, 1994AbstractSystemic lupus erythematosus is a disease that is particularly suited for studies of glomerular basement membrane pathology. Classification of the renal pathology of lupus nephritis is usually based on light microscopic features, combined with immunofluorescence findings and electron microscopic alterations.
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Glomerular Basement Membrane in Diabetics
American Journal of Clinical Pathology, 1966P, Kimmelstiel, G, Osawa, J, Beres
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Thin glomerular basement membrane disease.
Journal of nephrology, 2000The term thin glomerular basement membrane disease (TBMD) refers to a condition characterised by thinning of the GBM at electron microscopy examination and, clinically, by isolated hematuria, frequently occurring in other family members, with no extra-renal manifestations.
FRASCA' GM., ONETTI-MUDA A., RENIERI A.
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Thickness of Glomerular Basement Membranes
American Journal of Clinical Pathology, 1966G, Osawa, P, Kimmelstiel, V, Seiling
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Thin Glomerular Basement Membranes
American Journal of Kidney Diseases, 1999Fig 2. The diagnosis of thin basement membranes is made by electron microscopy. There is diffuse attenuation of the glomerular basement membrane, as illustrated here. In adults, basement membrane thickness less than 250 nm is indicative of thin basement membranes.
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Biochemistry of the Glomerular Basement Membrane in Diabetes
1973Publisher Summary This chapter discusses the biochemistry of the glomerular basement membrane in diabetes. The chapter describes a study of collagenase-Pronase glycopeptides from basement membrane that indicated that the amino acid constellation in the immediate vicinity of the linkage points of the disaccharide and heteropolysaccharide units differs
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