Results 171 to 180 of about 108,933 (325)

Polygonatum sibiricum Delar. ex Redoute: A Potential Functional Food for the Prevention and Treatment of Hyperuricemia

open access: yesFood Science &Nutrition, Volume 13, Issue 10, October 2025.
This study demonstrates that Polygonatum sibiricum (HJ) exhibits significant therapeutic potential for managing hyperuricemia (HUA), primarily through mechanisms involving the regulation of histidine metabolism via MAOA targets and the modulation of steroid hormone biosynthesis via CYP3A4, CYP1A2, and CYP1A1 targets.
Peng Zhao   +16 more
wiley   +1 more source

Anti-Glomerular Basement Membrane Disease With Thrombotic Thrombocytopenic Purpura

open access: yesCase Reports in Clinical Practice, 2019
We report a 25-year-old man who was initially presented with Rapidly Progressive Glomerulonephritis (RPGN) in Shahid Modarress Hospital, Tehran, Iran.
Amirhesam Alirezaei   +2 more
doaj  

Role of Neutrophils in Homeostasis and Diseases

open access: yesMedComm, Volume 6, Issue 10, October 2025.
Neutrophils are involved in the progression of various diseases through multiple mechanisms, including inflammatory responses, endothelial damage, and NETs release. (A) Cancer development and progression; (B) sepsis; (C) COVID‐19; (D) autoimmune diseases; (E) neurodegenerative diseases; (F) T2DM (e.g., diabetic foot ulcers (DFUs)); (G) nonalcoholic ...
Xingyu Chang   +3 more
wiley   +1 more source

Identification and characterization of novel glomerulus-associated genes and proteins [PDF]

open access: yes, 2010
The kidney is responsible for sieving the circulating blood to eliminate water-soluble waste products and potentially toxic substances from the body. The filtration step occurs in specialized filtration units called glomeruli.
Xiao, Zhijie
core  

Extracellular vesicles derived from silicate‐stimulated antler reserve mesenchymal cells alleviate kidney damage in diabetic nephropathy through inhibiting abnormal angiogenesis and apoptosis

open access: yesVIEW, Volume 6, Issue 5, October 2025.
A novel bioengineering platform was invented to harness simple silicate ions to command highly regenerative deer antler cells, transforming them into super‐factories that massively produce customized extracellular vesicles (Si‐RM‐EVs) rich in therapeutic miR‐148a‐3p, dwarfing natural EV output and payload.
Pengfei Hu   +9 more
wiley   +1 more source

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