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Anti-glomerular basement membrane vasculitis

Autoimmunity Reviews, 2023
Antiglomerular basement membrane disease (anti-GBM) is a rare life-threatening autoimmune vasculitis that involves small vessels and it is characterized by circulating autoantibodies directed against type IV collagen antigens expressed in glomerular and alveolar basement membrane.
Claudio, Ponticelli   +2 more
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Glomerular Basement Membrane Autoantibodies

2014
Partie 10, Chapitre 65 ; International ...
Luque-Paz, Damien   +2 more
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Glomerular Basement Membrane

2010
The glomerular basement membrane shown in panel A differs from basement membranes in other locations in that it is faced by a cell layer on either side, namely the endothelia and the podocytes and that it is thicker, because it is the product of fusion of the basement membrane of endothelial cells and podocytes.
Margit Pavelka, Jürgen Roth
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Dual origin of glomerular basement membrane

Developmental Biology, 1984
The histogenesis of renal basement membranes was studied in grafts of avascular, 11-day-old mouse embryonic kidney rudiments grown on chick chorioallantoic membrane (CAM). Vessels of the chick CAM invade the mouse tissue during an incubation period of 7-10 days and eventually hybrid glomeruli composed of mouse epithelium and chick endothelium form ...
Sariola, H   +6 more
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Molecular Sieving by Glomerular Basement Membrane

Nature, 1967
OF the three layers of the glomerular capillary wall—endothelial cells, basement membrane and epithelial cells—the basement membrane appears to be the only complete barrier between the plasma and the glomerular filtrate1,2. Support for the view that the basement membrane is the most important filtering mechanism was provided by the studies on ferritin ...
F, Huang, L, Hutton, N, Kalant
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Pathology of glomerular basement membrane nephropathy

Current Opinion in Nephrology and Hypertension, 1994
Studies of the molecular pathology of glomerular basement membrane have led to the discovery of four novel chains of type IV collagen, the latest of which is the alpha 6(IV) chain. Three chains have been shown to be directly involved in the pathogenesis of Goodpasture syndrome, Alport syndrome, and Alport posttransplantation antiglomerular basement ...
B G, Hudson, R, Kalluri, K, Tryggvason
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