Results 161 to 170 of about 600,020 (406)

Creatinine clearance and glomerular filtration rate [PDF]

Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2000
A number ofthreads' of comment about creatinine clearance ran on the ACB mailbase from April 1999. (There is a mail archive on the ACB web site, http://www.acb.org.uk.) Topics included the validity of urine measurement in patients with olig- uria; the effect of meat in the diet on creatinine production; formulae for calculating creatinine clearance ...
openaire   +3 more sources

THE RENAL EXCRETION OF INULIN AT LOW PLASMA CONCENTRATIONS OF THIS COMPOUND, AND ITS RELATIONSHIP TO THE GLOMERULAR FILTRATION RATE IN NORMAL, NEPHRITIC AND HYPERTENSIVE INDIVIDUALS 1 [PDF]

, 1940
Benjamin F. Miller, Alf S. Alving, Jack Rubin   +2 more
openalex   +1 more source

Generation of a new cystatin C-based estimating equation for glomerular filtration rate by use of 7 assays standardized to the international calibrator.

Clinical Chemistry, 2014
BACKGROUND Many different cystatin C-based equations exist for estimating glomerular filtration rate. Major reasons for this are the previous lack of an international cystatin C calibrator and the nonequivalence of results from different cystatin C ...
A. Grubb, M. Horio, L. Hansson, J. Björk, U. Nyman, M. Flodin, A. Larsson, A. Bökenkamp, Y. Yasuda, H. Blufpand, V. Lindström, I. Zegers, H. Althaus, S. Blirup-Jensen, Y. Itoh, P. Sjöström, G. Nordin, A. Christensson, H. Klima, Kathrin Sunde, Per Hjort-Christensen, D. Armbruster, C. Ferrero   +22 more
semanticscholar   +1 more source

Solanidine‐derived CYP2D6 phenotyping elucidates phenoconversion in multimedicated geriatric patients

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Phenoconversion, a genotype‐phenotype mismatch, challenges a successful implementation of personalized medicine. The aim of this study was to detect and determine phenoconversion using the solanidine metabolites 3,4‐seco‐solanidine‐3,4‐dioic acid (SSDA) and 4‐OH‐solanidine as diet‐derived cytochrome P450 2D6 (CYP2D6) biomarkers in a ...
Jens Andreas Sarömba, Julian Peter Müller, Jolanta Tupiec, Anjali Roeth, Berkan Kurt, Florian Kahles, Thea Laurentius, Cornelius Bollheimer, Julia C. Stingl, Katja S. Just   +9 more
wiley   +1 more source

Comparison of risk prediction using the CKD-EPI equation and the MDRD study equation for estimated glomerular filtration rate.

Journal of the American Medical Association (JAMA), 2012
CONTEXT The Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation more accurately estimates glomerular filtration rate (GFR) than the Modification of Diet in Renal Disease (MDRD) Study equation using the same variables, especially at ...
K. Matsushita, B. Mahmoodi, M. Woodward, J. Emberson, T. Jafar, S. Jee, K. Polkinghorne, A. Shankar, David H. Smith, M. Tonelli, D. Warnock, C. Wen, J. Coresh, R. Gansevoort, B. Hemmelgarn, A. Levey   +15 more
semanticscholar   +1 more source

The effect of severe renal impairment on the pharmacokinetics, safety and tolerability of balcinrenone

British Journal of Clinical Pharmacology, EarlyView.
Aims The aim of this phase 1 trial was to assess the pharmacokinetics, safety and tolerability of balcinrenone (previously AZD9977) in participants with severe renal impairment vs. those with normal renal function. Methods Participants with severe renal impairment (estimated glomerular filtration rate [eGFR] < 30 mL/min/1.73 m2) not on dialysis were ...
Chandrali S. Bhattacharya, Hans Ericsson, Susanne Johansson, Joanna Parkinson, Simina M. Boca, Ye Yang, Maria Heijer, Greggory Housler, Maria Leonsson‐Zachrisson, Judith Hartleib‐Geschwindner, Patricia Ely Pizzato   +10 more
wiley   +1 more source

A simple estimation of glomerular filtration rate in children

Paediatrica Indonesiana, 2002
Background The estimation of glomerular filtration rate (GFR) is routinely used in the assessment of renal function in children. An accurate measurement of GFR is very helpful in detecting renal disease.
Syarifuddin Rauf, Husein Akbar
doaj   +1 more source

Renal Blood Flow, Glomerular Filtration Rate, Renal PAH Extraction Ratio, and the Role of the Renal Vasomotor Nerves in the Unanesthetized Rabbit [PDF]

, 1963
PAUL I. Pascoe, Yvonne Körner
openalex   +1 more source

Paracetamol and its metabolites in children and adults with spinal muscular atrophy – a population pharmacokinetic model

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims The aim of the study was to investigate whether differences in paracetamol pharmacokinetics (PK) between spinal muscular atrophy (SMA) patients and healthy controls (HC) could be attributed to specific clinical covariates. Methods Nonlinear mixed‐effects modelling (NONMEM 7.4) was used to develop a population PK model, explore covariates ...
Qiaolin Zhao, Marie Mostue Naume, Brenda C. M. de Winter, Thomas Krag, Sissel Sundell Haslund‐Krog, Karoline Lolk Revsbech, John Vissing, Helle Holst, Morten Hylander Møller, Tessa Munkeboe Hornsyld, Morten Dunø, Christina Engel Hoei‐Hansen, Alfred Peter Born, Per Bo Jensen, Mette Cathrine Ørngreen   +14 more
wiley   +1 more source

The relationship between glomerular filtration rate and sodium reabsorption by the proximal tubule of the rat nephron [PDF]

, 1968
Barry M. Brenner, Cleaves M. Bennett, Robert W. Berliner   +2 more
openalex   +1 more source