Results 41 to 50 of about 475,296 (356)

The reduction of serum aminotransferase levels is proportional to the decline of the glomerular filtration rate in patients with chronic kidney disease [PDF]

, 2015
OBJECTIVE: This study sought to determine the serum aminotransferase levels of patients with predialysis chronic kidney disease and establish their relationships with serum creatinine levels and glomerular filtration rate.
Lopes, Edmundo Pessoa de Almeida, Sette, Luís Henrique Bezerra Cavalcanti   +1 more
core   +4 more sources

Inference and Prediction Using Functional Principal Components Analysis: Application to Diabetic Kidney Disease Progression in the Chronic Renal Insufficiency Cohort (CRIC) Study [PDF]

arXiv, 2022
Repeated longitudinal measurements are commonly used to model long-term disease progression, and timing and number of assessments per patient may vary, leading to irregularly spaced and sparse data. Longitudinal trajectories may exhibit curvilinear patterns, in which mixed linear regression methods may fail to capture true trends in the data.
arxiv  

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

Molecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever, Renske D. M. Steenbergen   +1 more
wiley   +1 more source

Prevalence of urolithiasis in Sarawak and associated risk factors: An ultrasonagraphy‐based cross‐sectional study

BJUI Compass, Volume 4, Issue 1, Page 74-80, January 2023., 2023
Abstract Objective The aim of this research is to study the prevalence of urolithiasis among the population of Sarawak Malaysia and the associated risk factors. Patients and Methods A survey was conducted among individuals aged ≥18 years age in three primary health care clinics in the main cities of Sarawak from March 2019 to March 2020.
Kamal Raj Perumal, Richelle Huey Bing Chua, Guan Chou Teh, Clarence Chang Moh Lei   +3 more
wiley   +1 more source

Linear mixed model vs two-stage methods: Developing prognostic models of diabetic kidney disease progression [PDF]

arXiv, 2022
Identifying prognostic factors for disease progression is a cornerstone of medical research. Repeated assessments of a marker outcome are often used to evaluate disease progression, and the primary research question is to identify factors associated with the longitudinal trajectory of this marker. Our work is motivated by diabetic kidney disease (DKD),
arxiv  

Tryptophan‐sensing receptor GPR142 expression levels are directly regulated by proinflammatory cytokines in ghrelin‐producing cells

FEBS Open Bio, EarlyView.
GPR142, a tryptophan‐sensing receptor, stimulates gastrointestinal hormones like ghrelin and is linked to inflammation regulation. Proinflammatory cytokines suppress ghrelin production, while tryptophan levels decrease via IDO1 activation. Our findings reveal that proinflammatory cytokines directly regulate GPR142 expression in ghrelin‐producing cells,
Yoko Ueda, Hiroshi Iwakura, Takuya Ensho, Mika Bando‐Shimizu, Asako Doi, Norihiko Matsutani, Shuhei Morita, Hidefumi Inaba, Hiroyuki Ariyasu, Naoki Fukuda, Keiji Hayata, Toshiyasu Ojima, Masahiro Nishi, Taka‐aki Matsuoka, Hiroki Yamaue, Takashi Akamizu   +15 more
wiley   +1 more source

Selective parenchymal clamping in open partial nephrectomy: Early experience with a low cost, reusable novel parenchymal clamp

BJUI Compass, Volume 4, Issue 1, Page 88-95, January 2023., 2023
Abstract Objectives The objective of this study is to present our initial experience with a novel parenchymal clamp (NPC) developed to allow partial nephrectomies (PN) to be performed without whole kidney ischaemia. We compare patients who underwent PN with the NPC with those undergoing standard PNs. Methods The NPC applies pressure only to the portion
James Macneil, Shuo Liu, Ramiz Iqbal, Finlay Macneil   +3 more
wiley   +1 more source

Relationship Between Gout Flare States and Patient‐Reported Outcomes After Allopurinol Initiation

Arthritis Care &Research, EarlyView.
Objective Gout flares are the most important clinical feature of the disease. A hypothetical maximum flare occurrence in the preceding six months has been suggested to be no flares for a patient‐acceptable symptom state (PASS) and only one flare for low disease activity (LDA).
Lisa K. Stamp, Chris Frampton, Sarah Stewart, Keith J. Petrie, N. Lawrence Edwards, Angelo Gaffo, Nicola Dalbeth   +6 more
wiley   +1 more source

Examination of Nephrotoxicity in Survivors of Childhood Cancer and Comparison of Methods for Estimating Glomerular Filtration Rate

Journal of Behçet Uz Children's Hospital, 2021
Objective: Increased survival rates in childhood cancers have led the researchers to focus on long-term side effects and possible risk factors for late nephrotoxicity related to the treatment regimens applied.
Arzu Yazal Erdem, Suna Emir, Nilgun Cakar, Hacı Ahmet Demir, Derya Özyörük   +4 more
doaj   +1 more source

PENGARUH SUPLEMENTASI KAPSUL EKSTRAK IKAN GABUS TERHADAP LAJU FILTRASI GLOMERULUS PADA SINDROM NEFROTIK RESISTEN STEROID ANAK [PDF]

, 2015
Background Steroid Resistant Nephrotic Syndrome (SRNS) is one of nephrotic syndrome classification which do not respond to therapy with steroid. Children with SRNS have high risk of decline of kidney’s function.
Ashila, Nisa, Muryawan, Heru
core