Results 41 to 50 of about 192,887 (307)

Magnetic Resonance Imaging‐Based Quantification of Endosomal Escape Using Iron Oxide Nanoparticle‐Loaded Lipid Nanoparticles

Advanced Healthcare Materials, EarlyView.
The therapeutic efficacy of lipid nanoparticle(LNP)‐based drugs depends on endosomal escape. However, few methods are available for quantifying the efficiency of endosomal escape in vivo. Herein, a novel method for quantifying the endosomal escape efficiency index using magnetic resonance imaging is introduced.
Somin Lee, Jeongbin Park, Han Na Jung, Shengjun Li, Zhijun Lin, Hyung‐Jun Im   +5 more
wiley   +1 more source

Serum cystatin C in estimating glomerular filtration rate [PDF]

Journal of Medical Biochemistry, 2008
Using serum cystatin C in estimating glomerular filtration rate (GFR) has in recent times been recommended. A number of simple formulas for calculating GFR have been derived specifically from serum cystatin C concentrations. The purpose of this study was
Čabarkapa Velibor, Stošić Zoran, Đerić Mirjana, Vučurević-Ristić Ljiljana, Žeravica Radmila, Ilinčić Branislava   +5 more
doaj  

Capillary‐Driven 3D Open Fluidic Networks for Versatile Continuous Flow Manipulation

Advanced Materials, EarlyView.
The capillary‐driven 3D open fluidic networks (OFNs), composed of connected polyhedral frames, enable precise, programmable, and versatile manipulation of unary, binary, and multiple continuous flows in both spatial and temporal dimensions. OFNs represent a significant leap beyond conventional microfluidics, unlocking new possibilities for selective ...
Shuangmei Wu, Siqi Sun, Jia Ye, Liqiu Wang, Yiyuan Zhang   +4 more
wiley   +1 more source

Biological and Biologically Inspired Functional Nanostructures: Insights into Structural, Optical, Thermal, and Sensing Applications

Advanced Materials, EarlyView.
Biological and biologically‐inspired functional nanostructures with structural, thermal, optical, and sensing applications are reviewed. The role of nanoscale features in biological materials on performance is described, and their blueprints are used for bio‐inspired nanomaterials, synthesized using advanced techniques (i.e., photolithography, bio ...
Chao Hsuan (Joseph) Sung, Taige Hao, Herry Fang, Andrew Tran Nguyen, Valentina Perricone, Haitao Yu, Wei Huang, Ezra Sarmiento, Adrian Francisco Duran Ornelas, Derek Lublin, Ric Wehling, Sanaz Farajollahi, Atsushi Arakaki, Dhriti Nepal, Nathan Patrick Lord, David Kisailus   +15 more
wiley   +1 more source

Renin-angiotensin system antagonists, glomerular filtration rate and blood pressure

Počki, 2018
The article deals with the mModern data on the influence of renin-angiotensin system blockers on the glomerular filtration rate, the level of arterial pressure and the outcome of chronic kidney disease.
D.D. Ivanov
doaj   +1 more source

Maternal glomerular filtration rate in pregnancy and fetal size. [PDF]

PLoS ONE, 2014
BACKGROUND: The relationship of maternal glomerular filtration rate (GFR) in pregnancy to fetal size needs to be better characterized as it impacts an ongoing debate about confounding effect of maternal GFR in investigations of important environmental ...
Nils-Halvdan Morken, Gregory S Travlos, Ralph E Wilson, Merete Eggesbø, Matthew P Longnecker   +4 more
doaj   +1 more source

[Estimating glomerular filtration rate]. [PDF]

Nederlands tijdschrift voor geneeskunde
Almost all laboratories in The Netherlands report an estimated glomerular filtration rate (eGFR) whenever a value for plasma creatinine is requested. This formula is based on gender and age, besides the plasma creatinine concentration, and sometimes also a correction for race is applied.
Vervloet, M.G., Smulders, Y.M.
openaire   +2 more sources

Integrative Omics Reveals Glutamine Catabolism‐Driven Apoptotic Suppression in Monocytes upon Mechanical Unloading

Advanced Science, EarlyView.
This research integrated multi‐omics analysis of bone tissue from HLU and control mice revealed that mechanical unloading suppresses intrinsic apoptosis and augments glutamine (Gln) catabolism in osteoclast lineage cells. The findings highlight pivotal roles for SLC1A5‐mediated Gln metabolism and XIAP/Diablo axis‐mediated apoptosis suppression.
Yi Ding, Fan Tong, Mingqiu Liu, Pin Yang, Jing Zeng, Yinghua Wei, Chunlin Li, Dong Li, Cheng Chang, Yangjun Zhang, Shaoqiong Yi, Fan Hu, Wenjie Shu, Lingqiang Zhang, Chun‐Ping Cui   +14 more
wiley   +1 more source

Magnetic Resonance Imaging–Derived Renal Oxygenation and Perfusion During Continuous, Steady‐State Angiotensin‐II Infusion in Healthy Humans

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundThe role of kidney hypoxia is considered pivotal in the progression of chronic kidney disease. A widely used method to assess kidney oxygenation is blood oxygen level dependent (BOLD)–magnetic resonance imaging (MRI), but its interpretation ...
René van der Bel, Bram F. Coolen, Aart J. Nederveen, Wouter V. Potters, Hein J. Verberne, Liffert Vogt, Erik S. G. Stroes, C. T. Paul Krediet   +7 more
doaj   +1 more source

Resident Macrophage‐Orchestrated Immune and Fibroblast Interactions in Immune Checkpoint Inhibitor‐Associated Nephrotoxicity

Advanced Science, EarlyView.
Schematic illustration of resident macrophages in Immune checkpoint inhibitor‐associated nephrotoxicity (ICI‐AN). Using an integrated approach (including imaging mass cytometry, transcriptomics, and murine models), this study reveals that resident macrophages drive immune‐stromal interactions in ICI‐AN, promoting fibroblast activation through CXCL9 and
Yanhong Ma, Yang Chen, Qinfan Yao, Yuxi Wang, Nan Ouyang, Fei Han, Guzong Wang, Meifang Wang, Yuan Yuan, Jianghua Chen, Jianzhen Shan, Dajin Chen   +11 more
wiley   +1 more source