Results 51 to 60 of about 416,019 (379)

Abemaciclib Inhibits Renal Tubular Secretion Without Changing Glomerular Filtration Rate

Clinical pharmacology and therapy, 2018
Abemaciclib, an inhibitor of cyclin dependent kinases 4 and 6, is indicated for metastatic breast cancer treatment. Reversible increases in serum creatinine levels of ~15–40% over baseline have been observed following abemaciclib dosing.
J. Chappell, P. Turner, Y. A. Pak, J. Bacon, A. Chiang, J. Royalty, Stephen D. Hall, P. Kulanthaivel, J. Bonventre   +8 more
semanticscholar   +1 more source

Risk of Hepatotoxicity in Patients With Gout Treated With Febuxostat or Benzbromarone: A Propensity Score–Matched Cohort Study

Arthritis Care &Research, EarlyView.
Objective The objective of this study was to evaluate and compare the risk of hepatotoxicity associated with the use of febuxostat and benzbromarone in patients with gout. Methods New users of febuxostat or benzbromarone with monitoring of liver function at least three times in a year after initiation of the study drugs were identified from an ...
Wenyan Sun, Lingling Cui, Robert Terkeltaub, Ying Chen, Xinde Li, Xiaoyu Cheng, Tian Liu, Nicola Dalbeth, Changgui Li   +8 more
wiley   +1 more source

Estimated glomerular filtration rate in observational and interventional studies in chronic kidney disease [PDF]

Estimated glomerular filtration rate is considered the principal measure of kidney function and, together with albuminuria, is a relevant prognostic factor for the development of end-stage kidney disease.
Abenavoli C., Baraldi O., Cianciolo G., Comai G., Coppolino G., De Nicola L., Hu L., La Manna G., Provenzano M.   +8 more
core   +1 more source

Colchicine Concentrations and Relationship With Colchicine Efficacy and Adverse Events: Post Hoc Analysis of a Randomized Clinical Trial of Colchicine for Gout Flare Prophylaxis

Arthritis Care &Research, EarlyView.
Objective Our objective was to examine the relationship between colchicine plasma concentrations and clinical and demographic factors and to determine the relationship between colchicine concentrations and colchicine efficacy and colchicine‐specific adverse events.
Lisa K. Stamp, Anne Horne, Borislav Mihov, Jill Drake, Janine Haslett, Peter Chapman, Daniel F. B. Wright, Christopher Frampton, Nicola Dalbeth   +8 more
wiley   +1 more source

Examination of Nephrotoxicity in Survivors of Childhood Cancer and Comparison of Methods for Estimating Glomerular Filtration Rate

Journal of Behçet Uz Children's Hospital, 2021
Objective: Increased survival rates in childhood cancers have led the researchers to focus on long-term side effects and possible risk factors for late nephrotoxicity related to the treatment regimens applied.
Arzu Yazal Erdem, Suna Emir, Nilgun Cakar, Hacı Ahmet Demir, Derya Özyörük   +4 more
doaj   +1 more source

Limited sampling strategies to estimate glomerular filtration rate in cats with low, normal and high glomerular filtration rates [PDF]

, 2010
C
Concordet, Didier, Croubels, Siska, Daminet, Sylvie, Lefebvre, Hervé P, Paepe, Dominique, Smets, Pascale, van Hoek, Ingrid   +6 more
core   +1 more source

Glomerular filtration rate and initiation of dialysis [PDF]

Canadian Medical Association Journal, 2010
In this issue, Clark and colleagues[1][1] present data showing a relationship between higher estimated glomerular filtration rate at the start of hemodialysis and mortality. Their results confirm the findings of previous observational studies.
Vianda S. Stel, Kitty J. Jager
openaire   +3 more sources

Extracorporeal Catalytic Hemoperfusion Therapy for Refractory Septic Shock Using Ceria Nanoparticle‐Embedded Porous Microbeads

Advanced Functional Materials, EarlyView.
This study introduces an extracorporeal hemoperfusion system incorporating porous microbeads embedded with autocatalytic ceria nanoparticles (CeNPs) for targeted reactive oxygen species (ROS) scavenging in septic shock. The blood‐compatible hemoperfusion cartridge demonstrated significant improvements in survival, hemodynamic stability, and organ ...
Pilseon Im, Han‐Gil Jeong, Donghee Kim, Jimin Song, Ngoc Man Phan, Eun‐seo Choi, Young‐Min Kim, Seo‐Hyeon Jeong, Jooho Park, Inwon Park, Jaeyun Kim   +10 more
wiley   +1 more source

Assessment of the Nova StatSensor whole blood point-of-care creatinine analyser for the measurement of kidney function in screening for chronic kidney disease [PDF]

, 2010
Point-of-care testing for creatinine using a fingerprick sample and resultant estimated glomerular filtration rate has potential for screening for chronic kidney disease in community settings.
Barbara, Jeffrey A J, Corso, Olivia, Mathew, Timothy, Mazzachi, Beryl C, Peake, Michael, Shephard, Anne Kathryn, Shephard, Mark Douglas, Spaeth, Brooke   +7 more
core  

Transdermal Measurement of Glomerular Filtration Rate in Mice

Journal of Visualized Experiments, 2018
Transdermal analysis of glomerular filtration rate (GFR) is an established technique that is used to assess renal function in mouse and rat models of acute kidney injury and chronic kidney disease.
Lauren Scarfe, Daniel Schock-Kusch, L. Ressel, Jochen Friedemann, Yury Shulhevich, P. Murray, B. Wilm, M. D. de Caestecker   +7 more
semanticscholar   +1 more source