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The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran+5 more
wiley +1 more source
Obstetric and long-term kidney outcomes in renal transplant recipients: a 40 year single-centre study [PDF]
Female renal transplant recipients of childbearing age may ask what the outcomes are for pregnancy and whether pregnancy will affect graft function. We analyzed obstetric and transplant outcomes among renal transplant recipients in our center who have ...
Brennand, Janet E.+6 more
core +1 more source
Transdermal Measurement of Glomerular Filtration Rate in Mice
Transdermal analysis of glomerular filtration rate (GFR) is an established technique that is used to assess renal function in mouse and rat models of acute kidney injury and chronic kidney disease.
Lauren Scarfe+7 more
semanticscholar +1 more source
The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali+5 more
wiley +1 more source
Prognostic significance of endogenous erythropoietin in long-term outcome of patients with acute decompensated heart failure [PDF]
Aims Although previous reports suggest that an elevated endogenous erythropoietin (EPO) level is associated with worse clinical outcomes in chronic heart failure (HF) patients, the prognostic implication of EPO in patients with acute decompensated HF ...
Anand+27 more
core +1 more source
Glomerular Filtration Rate Estimation Formulas for Pediatric and Neonatal Use.
Renal function assessment is of the utmost importance in predicting drug clearance and in ensuring safe and effective drug therapy in neonates. The challenges to making this prediction relate not only to the extreme vulnerability and rapid maturation of ...
Edit Muhari-Stark, G. Burckart
semanticscholar +1 more source
This study introduces an extracorporeal hemoperfusion system incorporating porous microbeads embedded with autocatalytic ceria nanoparticles (CeNPs) for targeted reactive oxygen species (ROS) scavenging in septic shock. The blood‐compatible hemoperfusion cartridge demonstrated significant improvements in survival, hemodynamic stability, and organ ...
Pilseon Im+10 more
wiley +1 more source
Glomerular filtration rate and initiation of dialysis [PDF]
In this issue, Clark and colleagues[1][1] present data showing a relationship between higher estimated glomerular filtration rate at the start of hemodialysis and mortality. Their results confirm the findings of previous observational studies.
Vianda S. Stel, Kitty J. Jager
openaire +3 more sources
Limited sampling strategies to estimate glomerular filtration rate in cats with low, normal and high glomerular filtration rates [PDF]
C
Concordet, Didier+6 more
core +1 more source
Acute kidney disease and renal recovery : consensus report of the Acute Disease Quality Initiative (ADQI) 16 Workgroup [PDF]
Consensus definitions have been reached for both acute kidney injury (AKI) and chronic kidney disease (CKD) and these definitions are now routinely used in research and clinical practice.
A Dewitte+173 more
core +2 more sources