Results 61 to 70 of about 416,019 (379)

Microphysiological Systems for Comorbidity Studies: Chronic Kidney Disease and Osteoarthritis

Advanced Healthcare Materials, EarlyView.
This review highlights the potential of organ‐on‐a‐chip systems for studying comorbidities, using chronic kidney disease (CKD) and osteoarthritis (OA) as examples. It summarizes recent advances in kidney‐on‐a‐chip and joint‐on‐a‐chip models and discusses their current and potential application in investigating CKD, OA, and CKD‐OA comorbidity, aiming to
Mingying Han, Weiping Lin, Yuanxiong Cao, Patricia Murray, Bettina Wilm, Stephen J McWilliam, Jude Curran, Ruoxiao Xie   +7 more
wiley   +1 more source

Effect of Blood Pressure Control on Long-Term Risk of End-Stage Renal Disease and Death Among Subgroups of Patients With Chronic Kidney Disease. [PDF]

, 2019
Background Our objective was to explore the effect of intensive blood pressure (BP) control on kidney and death outcomes among subgroups of patients with chronic kidney disease divided by baseline proteinuria, glomerular filtration rate, age, and body ...
Hsu, Chi-Yuan, Ku, Elaine, Lin, Feng, McCulloch, Charles E, Sarnak, Mark J, Smogorzewski, Miroslaw, Toto, Robert   +6 more
core  

Evaluation of estimated glomerular filtration rate and clinical variables in systemic sclerosis patients [PDF]

, 2016
Objectives: The most important renal complication of systemic sclerosis (SSc) is scleroderma renal crisis (SRC). Many patients demonstrate less severe renal complications, most likely associated with reduced renal blood flow and a consequent reduction in
Amoroso, Antonio, Barbano, Biagio, Cianci, Rosario, Gigante, Antonietta, Granata, Guido, Quarta, Silvia, Rosato, Edoardo, Salsano, Felice   +7 more
core   +1 more source

Glomerular Filtration Rate Estimation Formulas for Pediatric and Neonatal Use.

The Journal of Pediatric Pharmacology and Therapeutics, 2018
Renal function assessment is of the utmost importance in predicting drug clearance and in ensuring safe and effective drug therapy in neonates. The challenges to making this prediction relate not only to the extreme vulnerability and rapid maturation of ...
Edit Muhari-Stark, G. Burckart
semanticscholar   +1 more source

Biofabrication of a Filtration Barrier by Integrating Electrospun Membranes and Flow in a Glomerular Co‐Culture

Advanced Healthcare Materials, EarlyView.
An ex vivo glomerular filtration barrier is engineered using electrospun, biomimetic membranes seeded with human glomerular cells. The model supports fenestrated endothelium and podocyte foot processes under flow, mimics size‐selective filtration, and enables disease modeling with hiPSC‐derived podocytes, offering a powerful platform for studying ...
Camilla Mussoni, Anna Rederer, Vladimir Stepanenko, Frank Würthner, Philipp Stahlhut, Jürgen Groll, Mario Schiffer, Taufiq Ahmad, Janina Müller‐Deile   +8 more
wiley   +1 more source

Impairment in Glomerular Filtration Rate or Glomerular Filtration Barrier and Occurrence of Stroke [PDF]

Archives of Neurology, 2008
Chronic kidney disease (CKD) is associated with substantial burden and is a strong risk factor for cardiovascular disease. However, data on the relationship between CKD and stroke are few and are limited by unreliable or inadequate assessment of renal function.To properly assess the relationship between renal insufficiency and stroke in stroke ...
openaire   +3 more sources

Capillary‐Driven 3D Open Fluidic Networks for Versatile Continuous Flow Manipulation

Advanced Materials, EarlyView.
The capillary‐driven 3D open fluidic networks (OFNs), composed of connected polyhedral frames, enable precise, programmable, and versatile manipulation of unary, binary, and multiple continuous flows in both spatial and temporal dimensions. OFNs represent a significant leap beyond conventional microfluidics, unlocking new possibilities for selective ...
Shuangmei Wu, Siqi Sun, Jia Ye, Liqiu Wang, Yiyuan Zhang   +4 more
wiley   +1 more source

Differential Effects of Levosimendan and Dobutamine on Glomerular Filtration Rate in Patients With Heart Failure and Renal Impairment:A Randomized Double‐Blind Controlled Trial

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2018
Background The management of the cardiorenal syndrome in advanced heart failure is challenging, and the role of inotropic drugs has not been fully defined.
L. Lannemyr, S. Ricksten, B. Rundqvist, B. Andersson, S. Bartfay, C. Ljungman, P. Dahlberg, N. Bergh, C. Hjalmarsson, T. Gilljam, E. Bollano, K. Karason   +11 more
semanticscholar   +1 more source

A High‐Throughput AngioPlate Platform with Integrated AngioTEER for Modeling and Monitoring Renal Proximal Tubule Injury

Advanced Materials Technologies, EarlyView.
Renal tubular injury is a major contributor to kidney disease, yet remains poorly understood due to the lack of predictive models. This study presents a high‐throughput 3D renal proximal tubule model on the AngioPlate platform integrated with automated TEER measurements (AngioTEER), enabling real‐time monitoring of drug‐induced nephrotoxicity ...
Shravanthi Rajasekar, Anushree Chakravarty, Kimia Asadi Jozani, Brenda Truong, Matana Hendrickson, Ahmed Attia, Muna Sabouny, Anna Basatskaya, Sergi Clotet‐Freixas, Madeleine Ludlow, Alexander Sotra, Dawn S. Y. Lin, Feng Zhang, Boyang Zhang   +13 more
wiley   +1 more source

Evaluation of Glomerular Filtration Rate in Clinical Practice [PDF]

, 2003
peer reviewedGlomerular filtration rate (GFR) is the most frequently used parameter to evaluate the renal function. GFR may be estimated with serum creatinine, creatinine clearance based on 24 hours urine collection or Cockcroft formula.
Chapelle, Jean-Paul, Delanaye, Pierre, Ferir, Anne-Marie, Gielen, Jean-Louis, Krzesinski, Jean-Marie, Rorive, Georges   +5 more
core