Results 61 to 70 of about 475,296 (356)

Glomerular filtration rate in children with juvenile idiopathic arthritis

Zdorovʹe Rebenka, 2022
Today, it is proved that kidney injury in children with juvenile idiopathic arthritis (JIA) is characterized by a subclinical course and most often remains undiagnosed.
T.P. Borysova, S.V. Samsonenko
doaj   +1 more source

Estimated glomerular filtration rate and drug dose adjustment in patients in an intensive care unit in Brazil [PDF]

, 2020
Objectives. This study sought to compare the estimated glomerular filtration rate and the indication of dose adjustment of antimicrobials when using Cockcroft-Gault or Modification of Diet in Renal Disease. Methods.
Camargo, Marianne Silveira, Castro, Caroline Tianeze de, Mistro, Sostenes, Oliveira, Márcio Galvão, Passos, Luiz Carlos Santana, Rocha, Izabel Cristina Pereira, Santos, Camila Neto   +6 more
core   +1 more source

The Placenta Regulates Intrauterine Fetal Growth via Exosomal PPARγ

Advanced Science, EarlyView.
The placenta expresses much higher levels of PPARγ than fetal adipose tissue. Trophoblastic exosomes transport PPARγ into fetal preadipocytes via fetoplacental circulation and thus regulate adipogenic genes distinct from endogenous PPARγ. Compromised placental PPARγ leads to fetal adipogenesis deficiency and intrauterine growth restriction, reversible ...
Xiaofang Luo, Biao Huang, Ping Xu, Hao Wang, Baozhen Zhang, Li Lin, Jiujiang Liao, Mingyu Hu, Xiyao Liu, Jiayu Huang, Yong Fu, Mark D. Kilby, Rodney E. Kellems, Xiujun Fan, Yang Xia, Philip N. Baker, Hongbo Qi, Chao Tong   +17 more
wiley   +1 more source

Older patients with COVID‐19 and neuropsychiatric conditions: A study of risk factors for mortality

Brain and Behavior, Volume 12, Issue 12, December 2022., 2022
Abstract Background Little is known about risk factors for mortality in older patients with COVID‐19 and neuropsychiatric conditions. Methods We conducted a multicentric retrospective observational study at Assistance Publique‐Hôpitaux de Paris. We selected inpatients aged 70 years or older, with COVID‐19 and preexisting neuropsychiatric comorbidities
Vi‐Huong Nguyen‐Michel, Marion Houot, Cécile Delorme, Aude Sangaré, Ana Gales, Valerio Frazzini, Aurélie Hanin, Djamal Aissani, Thanh Trân, Bruno Oquendo, Flora Ketz, Carmelo Lafuente‐Lafuente, Christel Oasi, Kiyoka Kinugawa, Gaëlle Ouvrard, Renata Ursu, Bertrand Degos, Benjamin Rohaut, Sophie Demeret, Virginie Lambrecq, Vincent Navarro, Emmanuel Fournier, Jean‐Christophe Corvol, Alaina Borden   +23 more
wiley   +1 more source

Ultrasound characteristics and correlation with estimated glomerular filtration rate in patients with chronic kidney disease: A facility-based cross-sectional study

Journal of International Medical Research
Objective To evaluate grayscale sonographic characteristics and their correlation with the estimated glomerular filtration rate. Methodology: This cross-sectional study included 103 patients with stage III and above chronic kidney disease.
Fekadu H Getaneh, Bezamariam F Kassa, Lidet G Amha, Ferehiwot B Getaneh   +3 more
doaj   +1 more source

Differential Associations of Cystatin C Versus Creatinine‐Based Kidney Function With Risks of Cardiovascular Event and Mortality Among South Asian Individuals in the UK Biobank

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background South Asian individuals have increased cardiovascular disease and mortality risks. Reliance on creatinine‐ rather than cystatin C–based estimated glomerular filtration rate (eGFRcys) may underestimate the cardiovascular disease risk associated
Debbie C. Chen, Jennifer S. Lees, Kaiwei Lu, Rebecca Scherzer, Elaine Rutherford, Patrick B. Mark, Alka M. Kanaya, Michael G. Shlipak, Michelle M. Estrella   +8 more
doaj   +1 more source

Evaluation of an automated choroid segmentation algorithm in a longitudinal kidney donor and recipient cohort [PDF]

arXiv, 2023
Purpose: To evaluate the performance of an automated choroid segmentation algorithm in optical coherence tomography (OCT) data using a longitudinal kidney donor and recipient cohort. Methods: We assessed 22 donors and 23 patients requiring renal transplantation over up to 1 year post-transplant.
arxiv  

Postnatal maturation of the glomerular filtration rate in conventional growing piglets as potential juvenile animal model for preclinical pharmaceutical research [PDF]

, 2017
Adequate animal models are required to study the preclinical pharmacokinetics (PK), pharmacodynamics (PD) and safety of drugs in the pediatric subpopulation.
Croubels, Siska, Delanghe, Joris, Devreese, Mathias, Gasthuys, Elke, Heyndrickx, Marjolein, Millecam, Joske, Sys, Stanislas, Vande Walle, Johan, Vanderperren, Katrien   +8 more
core   +3 more sources

The Antiviral Efficacy and Safety of Azvudine in Hospitalized SARS‐CoV‐2 Infected Patients with Liver Diseases Based on a Multicenter, Retrospective Cohort Study

Advanced Science, EarlyView.
Azvudine shows benefits in reducing all‐cause mortality in hospitalized SARS‐CoV‐2 infected patients and liver diseases. COVID‐19 patients with kidney disease and without autoimmune diseases show a preference for azvudine. Azvudine may be a promising antiviral agent for treating COVID‐19 concomitant with liver diseases.
Junyi Sun, Mengzhao Yang, Guanyue Su, Ling Wang, Xiaobo Hu, Yongjian Zhou, Guangying Cui, Guowu Qian, Yiqiang Yuan, Xinjun Hu, Silin Li, Hong Luo, Shixi Zhang, Guangming Li, Donghua Zhang, Guotao Li, Ming Cheng, Zujiang Yu, Zhigang Ren   +18 more
wiley   +1 more source

Evidence of emerging BBB changes in mid‐age apolipoprotein E epsilon‐4 carriers

Brain and Behavior, Volume 12, Issue 12, December 2022., 2022
This study demonstrated a tendency towards BBB permeability in APOEε4 participants emerging from mid‐age, with quantitative differences observable on a number of the measures. Results from this study may help identify at‐risk populations at an early stage which will be crucial in facilitating the development of early interventions to change the ...
Nourah M. Alruwais, Jenifer M. Rusted, Naji Tabet, Nicholas G. Dowell   +3 more
wiley   +1 more source