Results 61 to 70 of about 192,887 (307)

Mapping Satellite Glial Cell Heterogeneity Reveals Distinct Spatial Organization and Implies Functional Diversity in the Dorsal Root Ganglion

Advanced Science, EarlyView.
Four distinct satellite glial cell subtypes are identified in mouse dorsal root ganglia using single‐cell RNA sequencing and spatial validation. These subtypes show unique marker profiles and anatomical distributions. Human dorsal root ganglia display layered perisomatic organization with differential marker expression.
Ole Andreas Ahlgreen, Mads Würgler Hansen, Jonas Baake, Thomas Engelbrecht Hybel, Rachele Rossi, Xin Lai, Ishwarya Sankaranarayanan, Johanne Amalie Pold, Lin Lin, Line Reinert, Søren Riis Paludan, Theodore John Price, Lone Tjener Pallesen, Christian Bjerggaard Vægter   +13 more
wiley   +1 more source

Genetically Engineered Light‐Responsive In Situ Hydrogels for Immunomodulation and Multimodal Therapy in Metastatic Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Cysteine‐tagged silk‐elastin‐like proteins, a family of tri‐block chimeric proteins that consist of a photothermal agent binding motif, silk motif, and elastin motif is developed to form a responsive in situ hydrogel for late‐stage and metastatic triple‐negative breast cancer.
Xinchen Shen, Jiajia Zhang, Junhan Ou, Ziheng Bai, Tongyan Liu, Kaiyue Zhang, Kaixiang Zhu, James Q. Wang, Chaochen Wang, Qianting Zhang, Linrong Lu, Wenwen Huang   +11 more
wiley   +1 more source

Long‐Term Nutritional Benefits of Laparoscopic Pancreatoduodenectomy Over Open Surgery

Annals of Gastroenterological Surgery, EarlyView.
Minimally invasive laparoscopic pancreaticoduodenectomy (LPD) significantly improves long‐term nutritional outcomes compared to open pancreaticoduodenectomy (OPD). LPD patients demonstrated better preservation of muscle mass index (PMI) and a lower incidence of postoperative fatty liver.
Koki Kurahashi, Takayuki Anazawa, Kei Yamane, Kazuyuki Nagai, Satoshi Ishida, Satoshi Ogiso, Yoichiro Uchida, Takashi Ito, Takamichi Ishii, Etsuro Hatano   +9 more
wiley   +1 more source

Impact of Intraoperative Fluid Volume on Complications After Minimally Invasive Esophagectomy: Analysis of 8782 Patients From the Japanese National Clinical Database

Annals of Gastroenterological Surgery, EarlyView.
This multicenter cohort study of 8782 esophagectomies in Japan found that higher intraoperative fluid volume significantly increased the risk of pneumonia after minimally invasive esophagectomy. Avoiding fluid overload may help reduce postoperative pneumonia.
Akihiko Okamura, Hideki Endo, Masayuki Watanabe, Hiroyuki Yamamoto, Hirotoshi Kikuchi, Naoki Yoshimura, Hideki Ueno, Masayuki Chida, Ken Shirabe   +8 more
wiley   +1 more source

Estimated glomerular filtration rate in patients overdosed with gentamicin

Journal of Laboratory Medicine, 2020
The aim of this study was to compare the estimated glomerular filtration rate (eGFR) from serum creatinine (eGFRcrea) and cystatin C (eGFRcys) in patients with elevated serum trough levels of gentamicin before the next planned dose during treatment in ...
Šálek Tomáš, Vodička Martin, Gabrhelík Tomáš   +2 more
doaj   +1 more source

Postoperative Impact of Anti‐Inflammatory Drug on Cancer Recurrence in Patients With Locally Advanced Gastric Cancer After Curative Gastrectomy: A Pilot Retrospective Study

Annals of Gastroenterological Surgery, EarlyView.
Anti‐inflammatory drugs may be effective in improving recurrence‐free survival after radical gastrectomy in patients with pStage II or III gastric cancer. ABSTRACT Background Elevated postoperative inflammation is associated with reduced recurrence‐free survival (RFS) after gastrectomy in patients with gastric cancer, independent of postoperative ...
Ryota Matsui, Manabu Ohashi, Motonari Ri, Rie Makuuchi, Masaru Hayami, Tomoyuki Irino, Takeshi Sano, Souya Nunobe   +7 more
wiley   +1 more source

Kidney functional changes over time in liver recipients

Трансплантология (Москва), 2018
Background. Glomerular filtration rate is the main parameter characterizing the kidney functional condition. The evaluation of glomerular filtration rate is of significant importance, since in addition to an objective indicator of the kidney functional ...
E. D. Kosmacheva, A. E. Babich
doaj   +1 more source

Intelligent Theranostic Systems Enabled by Aggregation‐Induced Emission in Precision Medicine

Aggregate, EarlyView.
Aggregation‐induced emission (AIE) luminogens are driving a new generation of intelligent theranostic systems that integrate high‐fidelity imaging and multifunctional therapy. This review highlights how AIEgens, through restriction of intramolecular motion (RIM), enable deep‐tissue NIR‐II imaging, ultrasensitive biosensing, CRISPR‐assisted gene ...
Qinqin Huang, Yanyu Chen, Shile Wang, Kan Liu, Xing‐Zhong Zhao, Xiaobo Mao, Ben Zhong Tang, Lang Rao   +7 more
wiley   +1 more source

Parameters Associated With Renal Recovery and Survival in Myeloma Patients With Acute Renal Failure to Cast Nephropathy

American Journal of Hematology, EarlyView.
Disease‐specific, patient‐specific, and treatment‐related factors correlate with renal recovery. ABSTRACT Acute renal failure due to cast nephropathy (CAN) is a severe complication of multiple myeloma (MM). Here, we aimed to identify parameters associated with renal outcomes and survival in newly diagnosed MM patients with CAN‐related acute renal ...
Heinz Ludwig, Meletios Athanasios Dimopoulos, Evangelos Terpos, Sarah Bernhard, Foteini Theodorakakou, Meral Beksac, Guldane Cengiz‐Seval, Nelson Leung, Luca Arcaini, Silvia Mangiacavalli, Frank Bridoux, Hermine Agis, Aristeidis Chaidos, Francesca Gay, Dario Roccatello, Wolfgang Hilbe, Andrea Havasi, Daniele Derudas, Nattawat Klomjit, Kenar D. Jhaveri, Javier De La Rubia Comos, Efstathios Kastritis   +21 more
wiley   +1 more source

THE RENAL EXCRETION OF INULIN AT LOW PLASMA CONCENTRATIONS OF THIS COMPOUND, AND ITS RELATIONSHIP TO THE GLOMERULAR FILTRATION RATE IN NORMAL, NEPHRITIC AND HYPERTENSIVE INDIVIDUALS 1 [PDF]

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Benjamin F. Miller, Alf S. Alving, Jack Rubin   +2 more
openalex   +1 more source