Results 71 to 80 of about 325,932 (347)

Olfactory‐to‐Entorhinal Network Dysrhythmias Drive Parkinson's Cognitive Impairment Through Frequency‐Specific Oscillatory Decoupling

Advanced Science, EarlyView.
Wang et al reveal that in the olfactory system, the selective impairment of gamma‐driven Barcode features underlying early olfactory deficits, while the selective impairment of theta‐driven Barcode features underlying later cognitive deficits, further establishing cross‐network gamma oscillations in the early stage as a biomarker of later cognitive ...
Shuaishuai Wang, Zhishen Cai, Xingfeng Mao, Yixuan Zhang, Yunlong Pan, Jiawen Cheng, Xuechun Wang, Hengyi Song, Sasaki Takuya, Ming Lu, Gang Hu, Xiuxiu Liu, Yingmei Lu, Feng Han   +13 more
wiley   +1 more source

Correlation of glomerular filtration rate and fibroblast growth factor-23 levels in chronic kidney disease; sub analysis chronic kidney disease–mineral and bone disorder study [PDF]

, 2022
Akiko Syawalidhany Tahir, Haerani Rasyid, Syakib Bakri, Hasyim Kasim, Tutik Harjianti, Muhammad Luthfi Parewangi, Harun Iskandar, Arifin Seweng   +7 more
openalex   +1 more source

Serum cystatin C is a sensitive early marker for changes in the glomerular filtration rate in patients undergoing laparoscopic surgery

Clinics, 2014
OBJECTIVE:Pneumoperitoneum during laparoscopy results in transient oliguria and decreased glomerular filtration and renal blood flow. The presence of oliguria and elevated serum creatinine is suggestive of acute renal injury.
Rodrigo Moreira e Lima, Lais Helena Camacho Navarro, Giane Nakamura, Daneshvari R. Solanki, Yara Marcondes Machado Castiglia, Pedro Tadeu Galvão Vianna, Eliana Marisa Ganem   +6 more
doaj   +1 more source

Renal Function Assessment Gap in Clinical Practice: An Awkward Truth

Kidney & Blood Pressure Research, 2020
Introduction: An accurate assessment of renal function is needed in the majority of clinical settings. Unfortunately, the most used estimated glomerular filtration rate (eGFR) formulas are affected by significant errors in comparison to gold standards ...
Francesco Trevisani, Federico Di Marco, Umberto Capitanio, Alessandro Larcher, Arianna Bettiga, Flaviano Dosio, Michele Ghidini, Gianluca Del Conte, Riccardo Vago, Alessandra Cinque, Luigi Gianolli, Andrea Salonia, Alberto Briganti, Sergio Luis-Lima, Natalia Negrín-Mena, Francesco Montorsi, Esteban Porrini   +16 more
doaj   +1 more source

Tubule‐Derived IFN‐α Promotes GSDMD‐Mediated Macrophage Pyroptosis to Drive Renal Inflammation and Fibrosis Through JAK2/STAT2 Activation

Advanced Science, EarlyView.
Mao and colleagues uncover a STAT2/IRF9‐dependent signaling axis through which tubular epithelial cell (TEC)‐derived IFN‐α induces gasdermin D (GSDMD)‐mediated pyroptosis in macrophages. This TEC‐macrophage feedback loop amplifies renal inflammation and fibrosis, providing mechanistic insight into the progression of chronic kidney disease and revealing
Yiping Xu, Yating Wang, Siming Jiang, Yi Li, Guanglan Li, Yuchu Liu, Siyuan Li, Yiming Zhou, Qinghua Liu, Yi Zhou, Wei Chen, Hongyu Li, Haiping Mao   +12 more
wiley   +1 more source

Elevated Plasma Free Sialic Acid Levels in Individuals with Reduced Glomerular Filtration Rates [PDF]

, 2020
Federico Fuentes, Nuria Carrillo, Kenneth J. Wilkins, J. Thomas Blake, Petcharat Leoyklang, William A. Gahl, Jeffrey B. Kopp, Marjan Huizing   +7 more
openalex   +1 more source

Estimated Glomerular Filtration Rate and the Risk of Cancer.

American Society of Nephrology. Clinical Journal, 2019
BACKGROUND AND OBJECTIVES Community-based reports regarding eGFR and the risk of cancer are conflicting. We here explore plausible links between kidney function and cancer incidence in a large Scandinavian population-based cohort.
Hong Xu, K. Matsushita, G. Su, Marco Trevisan, J. Ärnlöv, P. Bárány, B. Lindholm, C. Elinder, M. Lambe, J. Carrero   +9 more
semanticscholar   +1 more source

Dipiperazine‐Phenyl Derivatives Based on Convergent Molecular Platforms Can Reverse Multidrug Resistance in Gram‐Negative Bacteria by Inhibiting Efflux and Permeabilizing Cell Membranes

Advanced Science, EarlyView.
By integrating a convergent molecular platform strategy, this study designed a novel dual‐target C5 to combat multidrug‐resistant Gram‐negative bacteria. C5 synergistically enhances antibiotic efficacy by inhibiting efflux pumps and increasing bacterial membrane permeability.
Jiale Dong, Ting Guo, Yi Huang, Yangchun Ma, Weijin Chen, Jie Xue, Jun Jiang, Enhui Dong, Yue Kong, Hang Ding, Wenlong Zhang, Shutao Ma   +11 more
wiley   +1 more source

Effect of sex on glomerular filtration rate in programmed rats by prenatal dexamethasone

Physiological Reports, 2019
We have previously demonstrated that dexamethasone administered to pregnant rats during specific times during gestation results in a reduction in glomerular number and hypertension in offspring at 2 and 6 months of age.
Jyoti Jain, Susan K. Legan, Issa Alhamoud, Jyothsna Gattineni, Michel Baum   +4 more
doaj   +1 more source

Ultrasound‐Boosted Liposomal Prodrug Overcomes Age‐Associated Biodistribution Disparity in Pediatric Solid Tumor Therapy

Advanced Science, EarlyView.
The age‐associated disparity of nanocarrier biodistribution limits the nanotherapeutics of childhood solid tumors. This study developed an ultrasound‐activated liposomal prodrug (CSCPTL) to overcome the age‐associated disparity of off‐target distribution.
Danfei Chen, Junjun Xu, Jian Chen, Jue Hu, Xiaobo Xuan, Haifang Cai, Mingdong Yang, Zhuxian Zhou, Guowei Wang   +8 more
wiley   +1 more source