Evaluation of Biomarker-Based Glomerular Filtration Rate Estimating Equations in Glomerular Disease
Introduction: Glomerular filtration rate (GFR) is typically estimated with equations that use biomarkers such as serum creatinine and/or cystatin-C. The impact of these different biomarkers on GFR estimates in glomerular disease patients is unclear.
Antara Mondal+3 more
doaj +1 more source
Effect of sex on glomerular filtration rate in programmed rats by prenatal dexamethasone
We have previously demonstrated that dexamethasone administered to pregnant rats during specific times during gestation results in a reduction in glomerular number and hypertension in offspring at 2 and 6 months of age.
Jyoti Jain+4 more
doaj +1 more source
Renin-angiotensin system antagonists, glomerular filtration rate and blood pressure
The article deals with the mModern data on the influence of renin-angiotensin system blockers on the glomerular filtration rate, the level of arterial pressure and the outcome of chronic kidney disease.
D.D. Ivanov
doaj +1 more source
Maternal glomerular filtration rate in pregnancy and fetal size. [PDF]
BACKGROUND: The relationship of maternal glomerular filtration rate (GFR) in pregnancy to fetal size needs to be better characterized as it impacts an ongoing debate about confounding effect of maternal GFR in investigations of important environmental ...
Nils-Halvdan Morken+4 more
doaj +1 more source
Incomplete reversibility of estimated glomerular filtration rate decline following tenofovir disoproxil fumarate exposure. [PDF]
BACKGROUND: Tenofovir disoproxil fumarate (TDF) has been linked to renal impairment, but the extent to which this impairment is reversible is unclear. We aimed to investigate the reversibility of renal decline during TDF therapy.
Campbell, LJ+16 more
core +2 more sources
GABP Promotes Mesangial Cell Proliferation and Renal Fibrosis Through GLI1 in Diabetic Nephropathy
GABP is found to promote mesangial cell proliferation and ECM deposition through GLI1, while inhibiting GABP or GLI1 prevents the progression of DN by reducing ECM and fibrosis. The research results indicate that a potential therapeutic approach based on inhibiting mesangial cell proliferation and ECM accumulation can effectively treat DN, while GABP ...
Lei Du+11 more
wiley +1 more source
Post-kidney donation glomerular filtration rate measurement and estimation
Background: Long-term consequences associated with kidney donation are controversial. Pre- and post-donation glomerular filtration rates (GFRs) are determinants of renal and cardiovascular risk weighting.
Pablo Luján+5 more
doaj
BackgroundThe role of kidney hypoxia is considered pivotal in the progression of chronic kidney disease. A widely used method to assess kidney oxygenation is blood oxygen level dependent (BOLD)–magnetic resonance imaging (MRI), but its interpretation ...
René van der Bel+7 more
doaj +1 more source
Automatic Classification of Irregularly Sampled Time Series with Unequal Lengths: A Case Study on Estimated Glomerular Filtration Rate [PDF]
A patient's estimated glomerular filtration rate (eGFR) can provide important information about disease progression and kidney function. Traditionally, an eGFR time series is interpreted by a human expert labelling it as stable or unstable. While this approach works for individual patients, the time consuming nature of it precludes the quick evaluation
arxiv
Limited sampling strategies to estimate glomerular filtration rate in cats with low, normal and high glomerular filtration rates [PDF]
C
Concordet, Didier+6 more
core +1 more source